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CHROMANOL 293B structure, CAS 163163-23-3

CHROMANOL 293B

CAS Number163163-23-3

SynonymsMFCD06798368; Chromanol 293B; 293B Cpd

Molecular FormulaC15H20N2O4S

Molecular Weight324.39500

Purity98.00%

Density1.33g/cm3

Boiling Point474.1ºC at 760mmHg

Melting Point

Flash Point

Appearancesolid

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-1171432 Purity: 98.00%
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Quality Control of [ 163163-23-3 ] Purity: 98.00% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number163163-23-3
Catalog No.2A-1171432
Chinese Name色原烷醇293B
SynonymsMFCD06798368; Chromanol 293B; 293B Cpd
Molecular FormulaC15H20N2O4S
Molecular Weight324.39500
Purity98.00
Density1.33g/cm3
Boiling Point474.1ºC at 760mmHg
Appearancesolid
Storage Condition20°C
ApplicationChromol 293B is a selective blocker of slow delayed rectifier potassium currents (IKs) with an IC50 of 1-10 μM and a weak inhibitor of KATP channels. Chromanol 293B also blocks CFTR chloride currents
PubChem ID854065
SMILESCCS(=O)(=O)N(C)C1c2cc(C#N)ccc2OC(C)(C)C1O
InChIInChI=1S/C15H20N2O4S/c1-5-22(19,20)17(4)13-11-8-10(9-16)6-7-12(11)21-15(2,3)14(13)18/h6-8,13-14,18H,5H2,1-4H3/t13-,14+/m0/s1
InChI KeyHVSJHHXUORMCGK-UONOGXRCSA-N
Hazard Symbolstransportation
MSDSmsds/171632_2_163163_23_3.pdf
BioactivityChromanol 293B is a selective blocker of the slow delayed rectifier K+ current (IKs) with IC50 of 1-10 μM and a weak inhibitor of KATP channel. Chromanol 293B also blocks the CFTR chloride current with an IC50 of 19 μM[1]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> CFTR Research Areas >> Cardiovascular Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel References [1]. Bachmann A, Quast U, Russ U. Chromanol 293B, a blocker of the slow delayed rectifier K+ current (IKs), inhibits the CFTR Cl- current. Naunyn Schmiedebergs Arch Pharmacol. 2001 Jun;363(6):590-6. Chemical & Physical Properties Density 1.33g/cm3 Boiling Point 474.1ºC at 760mmHg Molecular Formula C15H20N2O4S Molecular Weight 324.39500 Exact Mass 324.11400 PSA 99.01000 LogP 2.49358 Vapour Pressure 8.52E-10mmHg at 25°C Index of Refraction 1.592 InChIKey HVSJHHXUORMCGK-UONOGXRCSA-N SMILES CCS(=O)(=O)N(C)C1c2cc(C#N)ccc2OC(C)(C)C1O Storage condition 20°C
Use ofChromanol 293B is a selective blocker of the slow delayed rectifier K+ current (IKs) with IC50 of 1-10 μM and a weak inhibitor of KATP channel. Chromanol 293B also blocks the CFTR chloride current with an IC50 of 19 μM[1]. Properties Articles31 Name N-[(3R,4S)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-N-methylethanesulfonamide Synonym More Synonyms Chromanol 293B Biological Activity Description Chromanol 293B is a selective blocker of the slow delayed rectifier K+ current (IKs) with IC50 of 1-10 μM and a weak inhibitor of KATP channel. Chromanol 293B also blocks the CFTR chloride current with an IC50 of 19 μM[1]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> CFTR Research Areas >> Cardiovascular Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel References [1]. Bachmann A, Quast U, Russ U. Chromanol 293B, a blocker of the slow delayed rectifier K+ current (IKs), inhibits the CFTR Cl- current. Naunyn Schmiedebergs Arch Pharmacol. 2001 Jun;363(6):590-6. Chemical & Physical Properties Molecular Formula C15H20N2O4S Exact Mass 324.11400 PSA 99.01000 LogP 2.49358 Index of Refraction 1.592 InChIKey HVSJHHXUORMCGK-UONOGXRCSA-N
Transport InfoProduct name: Purity: 99.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
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