
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 885060-09-3 |
| Catalog No. | 2A-1171039 |
| Chinese Name | (2S)-2-(3-氨基丙基)-5-(2,5-二氟苯基)-N-甲氧基-N-甲基-2-苯基-1,3,4-噻二唑-3(2H)-甲酰胺 |
| Synonyms | UNII-8A49OSO368; CS-0867; ARRY 520 trifluoroacetate; UNII: 8A49OSO368; ARRY-520; Filanesib; Filanesib [INN] |
| Molecular Formula | C20H22F2N4O2S |
| Molecular Weight | 420.476 |
| Purity | 98.00% |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 511.3±60.0 °C at 760 mmHg |
| Storage Condition | 2-8℃ |
| Application | Filanesib (ARRY-520) is a synthetic inhibitor of spindle kinesin (KSP) with an IC50 of 6 nM. |
| PubChem ID | 85240789 |
| SMILES | CON(C)C(=O)N1N=C(c2cc(F)ccc2F)SC1(CCCN)c1ccccc1 |
| InChI | InChI=1S/C20H22F2N4O2S/c1-25(28-2)19(27)26-20(11-6-12-23,14-7-4-3-5-8-14)29-18(24-26)16-13-15(21)9-10-17(16)22/h3-5,7-10,13H,6,11-12,23H2,1-2H3/t20-/m0/s1 |
| InChI Key | LLXISKGBWFTGEI-FQEVSTJZSA-N |
| Transport Info | Product name: ARRY-520 |
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