CAS Number1353016-71-3
SynonymsDBCO-NHS ester; Dibenzylcyclooctyne-NHS ester; Dibenzocyclooctyne-N-hydroxysuccinimidyl ester; DBCO-succinyl N-hydroxysuccinimidyl ester; 2,5-dioxopyrrolidin-1-yl 4-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate; 2,5-dioxopyrrolidin-1-yl 4-(didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate
Molecular FormulaC23H18N2O5
Molecular Weight402.39900
Purity98.00%
Density1.43±0.1 g/cm3
Boiling Point670.2±65.0 °C at 760 mmHg
AppearanceBeige or light gray loose solid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1353016-71-3 |
| Catalog No. | 2A-1170633 |
| Chinese Name | 4-[(5-氮杂-3,4:7,8-二苯并环辛-1-炔)-5-基]-4-氧代丁酸-N-琥珀酰亚胺酯 |
| Synonyms | DBCO-NHS ester; Dibenzylcyclooctyne-NHS ester; Dibenzocyclooctyne-N-hydroxysuccinimidyl ester; DBCO-succinyl N-hydroxysuccinimidyl ester; 2,5-dioxopyrrolidin-1-yl 4-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate; 2,5-dioxopyrrolidin-1-yl 4-(didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate |
| Molecular Formula | C23H18N2O5 |
| Molecular Weight | 402.39900 |
| Purity | 98.00 |
| Density | 1.43±0.1 g/cm3 |
| Boiling Point | 670.2±65.0 °C at 760 mmHg |
| Appearance | Beige or light gray loose solid |
| Storage Condition | 2-8℃ |
| Application | DBCO-NHS ester is a cleavable ADC bridge for the synthesis of antibody drug conjugates (ADCs). |
| PubChem ID | 201759211 |
| SMILES | O=C(CCC(=O)N1Cc2ccccc2C#Cc2ccccc21)ON1C(=O)CCC1=O |
| InChI | InChI=1S/C23H18N2O5/c26-20(13-14-23(29)30-25-21(27)11-12-22(25)28)24-15-18-7-2-1-5-16(18)9-10-17-6-3-4-8-19(17)24/h1-8H,11-15H2 |
| InChI Key | XCEBOJWFQSQZKR-UHFFFAOYSA-N |
| Transport Info | Product name: DBCO-NHS ester |
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