| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1029044-16-3 |
| Catalog No. | 2A-1170329 |
| Chinese Name | 吡昔替尼 |
| Synonyms | PLX3397; PLX-3397; pexidartinib |
| Molecular Formula | C20H15ClF3N5 |
| Molecular Weight | 417.815 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 580.0±50.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | Pexidartinib (PLX-3397) is a multi-target receptor tyrosine kinase inhibitor with IC50s of 13 nM, 27 nM and 11 nM for inhibiting CSF1R, c-Kit and FLT3 respectively. |
| PubChem ID | 57245138 |
| SMILES | FC(F)(F)c1ccc(CNc2ccc(Cc3c[nH]c4ncc(Cl)cc34)cn2)cn1 |
| InChI | InChI=1S/C20H15ClF3N5/c21-15-6-16-14(10-28-19(16)29-11-15)5-12-2-4-18(26-7-12)27-9-13-1-3-17(25-8-13)20(22,23)24/h1-4,6-8,10-11H,5,9H2,(H,26,27)(H,28,29) |
| InChI Key | JGWRKYUXBBNENE-UHFFFAOYSA-N |
| Transport Info | Product Name: Pexidartinib |
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