Home > Products > Rubber & Polymer Chemicals > Plastic & Specialty Additives > N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide

N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide

Name: N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide
Brand: 2A Biotech
SKU: 2A-1170286

CAS Number871700-17-3

SynonymsUNII-33E86K87QN; GSK 1120212; GSK-1120212; Mekinist; GSK1120212; JTP74057; Trametinib

Molecular FormulaC26H23FIN5O4

Molecular Weight615.395

Density1.7±0.1 g/cm3

AppearanceWhite to off-white solid

MSDSChinese English

Cat. No.: 2A-1170286 Purity:

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Quality Control of [ 871700-17-3 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	871700-17-3
Catalog No.	2A-1170286
Chinese Name	曲美替尼
Synonyms	UNII-33E86K87QN; GSK 1120212; GSK-1120212; Mekinist; GSK1120212; JTP74057; Trametinib
Molecular Formula	C26H23FIN5O4
Molecular Weight	615.395
Density	1.7±0.1 g/cm3
Appearance	White to off-white solid
Storage Condition	2-8°C
Application	Trametinib DMSO solvate is a potent MEK inhibitor with an IC50 of approximately 2 nM for MEK1 and MEK2. Due to the poor solubility of Trametinib, it is more recommended to use Trametinib DMSO solvate
HTC	29339900
SMILES	CC(=O)Nc1cccc(-n2c(=O)n(C3CC3)c(=O)c3c(Nc4ccc(I)cc4F)n(C)c(=O)c(C)c32)c1
InChI Key	LIRYPHYGHXZJBZ-UHFFFAOYSA-N
Transport Info	Product Name: Trametinib (GSK1120212)

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N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide

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