
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1643913-93-2 |
| Catalog No. | 2A-1170263 |
| Chinese Name | KPT-9274 |
| Synonyms | PAK4-IN-1; KPT-9274 |
| Molecular Formula | C35H29F3N4O3 |
| Molecular Weight | 610.625 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 857.5±65.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | KPT-9274 is an orally active PAK4/nicotinamide phosphoribosyltransferase (Nampt) inhibitor with IC50 values of less than 100 and 125 nM, respectively. |
| PubChem ID | 311150288 |
| SMILES | Nc1ccc(C=CC(=O)NCc2cc3cc(-c4ccc(C(=O)N5CCC(F)(F)CC5)cc4)cc(-c4ccc(F)cc4)c3o2)cn1 |
| InChI | InChI=1S/C35H29F3N4O3/c36-28-9-7-24(8-10-28)30-19-26(23-3-5-25(6-4-23)34(44)42-15-13-35(37,38)14-16-42)17-27-18-29(45-33(27)30)21-41-32(43)12-2-22-1-11-31(39)40-20-22/h1-12,17-20H,13-16,21H2,(H2,39,40)(H,41,43)/b12-2+ |
| InChI Key | MRFOPLWJZULAQD-SWGQDTFXSA-N |
| Transport Info | Product name: KPT 9274 (ATG-019) |
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