KPT-9294 structure, CAS 1643913-93-2

KPT-9294

CAS Number1643913-93-2

SynonymsPAK4-IN-1; KPT-9274

Molecular FormulaC35H29F3N4O3

Molecular Weight610.625

Purity

Density1.4±0.1 g/cm3

Boiling Point857.5±65.0 °C at 760 mmHg

Melting Point

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-1170263 Purity:
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Quality Control of [ 1643913-93-2 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number1643913-93-2
Catalog No.2A-1170263
Chinese NameKPT-9274
SynonymsPAK4-IN-1; KPT-9274
Molecular FormulaC35H29F3N4O3
Molecular Weight610.625
Density1.4±0.1 g/cm3
Boiling Point857.5±65.0 °C at 760 mmHg
Appearancepowder
Storage Condition-20℃
ApplicationKPT-9274 is an orally active PAK4/nicotinamide phosphoribosyltransferase (Nampt) inhibitor with IC50 values ​​of less than 100 and 125 nM, respectively.
PubChem ID311150288
SMILESNc1ccc(C=CC(=O)NCc2cc3cc(-c4ccc(C(=O)N5CCC(F)(F)CC5)cc4)cc(-c4ccc(F)cc4)c3o2)cn1
InChIInChI=1S/C35H29F3N4O3/c36-28-9-7-24(8-10-28)30-19-26(23-3-5-25(6-4-23)34(44)42-15-13-35(37,38)14-16-42)17-27-18-29(45-33(27)30)21-41-32(43)12-2-22-1-11-31(39)40-20-22/h1-12,17-20H,13-16,21H2,(H2,39,40)(H,41,43)/b12-2+
InChI KeyMRFOPLWJZULAQD-SWGQDTFXSA-N
Transport InfoProduct name: KPT 9274 (ATG-019)
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