
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 125973-56-0 |
| Catalog No. | 2A-1170203 |
| Chinese Name | 4-(3,5-双(三甲基硅烷基)苯甲酰氨基)苯甲酸 |
| Synonyms | Am-555S; 4-{[3,5-Bis(trimethylsilyl)benzoyl]amino}benzoic acid; Amsilarotene; TAC 101 |
| Molecular Formula | C20H27NO3Si2 |
| Molecular Weight | 385.604 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 403.3±45.0 °C at 760 mmHg |
| Appearance | solid |
| Storage Condition | room temperature, inert gas |
| Application | Amsilarotene (TAC-101; Am 555S) is an orally active synthetic retinoic acid with a selective affinity of 2.4400 nm for retinoic acid receptor α (RAR-α) and the Ki of RAR-α and RAR-β. Ammoniasilane can |
| SMILES | C[Si](C)(C)c1cc(C(=O)Nc2ccc(C(=O)O)cc2)cc([Si](C)(C)C)c1 |
| InChI | InChI=1S/C20H27NO3Si2/c1-25(2,3)17-11-15(12-18(13-17)26(4,5)6)19(22)21-16-9-7-14(8-10-16)20(23)24/h7-13H,1-6H3,(H,21,22)(H,23,24) |
| InChI Key | VVTNSTLJOVCBDL-UHFFFAOYSA-N |
| Transport Info | Product Name: Amsilarotene |
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