
CAS Number70-78-0
Synonyms3-Iodotyrosine; EINECS 200-744-8; 3-IODO-L-TYROSINE; MFCD00002608; Monoiodotyrosine; 3-Monoiodo-L-tyrosine; H-Tyr(3-I)-OH
Molecular FormulaIC6H3-4-(OH)CH2CH(NH2)CO2H
Molecular Weight307.09
Purity98.00%
Density1.9±0.1 g/cm3
Boiling Point391.0±42.0 °C at 760 mmHg
Melting Point210 °C (dec.) (lit.)
Appearancewhite solid
EINECS200-744-8
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 70-78-0 |
| Catalog No. | 2A-9017010 |
| Chinese Name | 3-碘-L-酪氨酸 |
| Synonyms | 3-Iodotyrosine; EINECS 200-744-8; 3-IODO-L-TYROSINE; MFCD00002608; Monoiodotyrosine; 3-Monoiodo-L-tyrosine; H-Tyr(3-I)-OH |
| Molecular Formula | IC6H3-4-(OH)CH2CH(NH2)CO2H |
| Molecular Weight | 307.09 |
| Purity | 98.00 |
| Density | 1.9±0.1 g/cm3 |
| Boiling Point | 391.0±42.0 °C at 760 mmHg |
| Melting Point | 210 °C (dec.) (lit.) |
| Appearance | white solid |
| Water Solubility | dilute aqueous acid: soluble |
| Storage Condition | This product should be sealed and stored in a dry |
| Application | H-Tyr(3-I)-OH is a potent inhibitor of tyrosine hydroxylase. |
| EINECS | 200-744-8 |
| HTC | 2922509090 |
| PubChem ID | 24278154 |
| MDL Number | MFCD00002608 |
| SMILES | N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O |
| InChI | 1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1 |
| InChI Key | UQTZMGFTRHFAAM-ZETCQYMHSA-N |
| Beilstein/REAXYS | 2941266 |
| NACRES Code | NA.32 |
| eCl@ss | 32160406 |
| UNSPSC | 12352200 |
| Hazard Symbols | Transport |
| MSDS | msds/17010_1_70_78_0.pdf |
| Bioactivity | H-Tyr(3-I)-OH is an effective tyrosine hydroxylase inhibitor. Related Catalog Natural Products >> Acids and Aldehydes Research Areas >> Others Target Human Endogenous Metabolite In Vitro H-Tyr(3-I)-OH (3-iodo-L-tyrosine) is as effective inhibitor of tyrosine hydroxylase. At a concentration of 100μM 3-iodo-L-tyrosine inhibits the enzymatic activity 100% and at a concentration of 10μM it inhibits 60-70%[1]. References [1]. GOLDSTEIN M, et al. INHIBITION OF TYROSINE HYDROXYLASE BY 3-IODO-L-TYROSINE. Life Sci (1962). 1965 Jan;4:261-4. Chemical & Physical Properties Density 1.9±0.1 g/cm3 Boiling Point 391.0±42.0 °C at 760 mmHg Melting Point 210 °C (dec.)(lit.) Molecular Formula C9H10INO3 Molecular Weight 307.085 Flash Point 190.3±27.9 °C Exact Mass 306.970520 PSA 83.55000 LogP 1.54 Vapour Pressure 0.0±0.9 mmHg at 25°C Index of Refraction 1.689 InChIKey UQTZMGFTRHFAAM-ZETCQYMHSA-N SMILES NC(Cc1ccc(O)c(I)c1)C(=O)O Storage condition 2-8°C Water Solubility dilute aqueous acid: soluble |
| Use of | H-Tyr(3-I)-OH is an effective tyrosine hydroxylase inhibitor. Properties Articles22 Name 3-iodo-L-tyrosine Synonym More Synonyms 3-Iodo-L-tyrosine Biological Activity Description H-Tyr(3-I)-OH is an effective tyrosine hydroxylase inhibitor. Related Catalog Natural Products >> Acids and Aldehydes Research Areas >> Others Human Endogenous Metabolite In Vitro H-Tyr(3-I)-OH (3-iodo-L-tyrosine) is as effective inhibitor of tyrosine hydroxylase. At a concentration of 100μM 3-iodo-L-tyrosine inhibits the enzymatic activity 100% and at a concentration of 10μM it inhibits 60-70%[1]. References [1]. GOLDSTEIN M, et al. INHIBITION OF TYROSINE HYDROXYLASE BY 3-IODO-L-TYROSINE. Life Sci (1962). 1965 Jan;4:261-4. Chemical & Physical Properties Molecular Formula C9H10INO3 Exact Mass 306.970520 PSA 83.55000 Index of Refraction 1.689 InChIKey UQTZMGFTRHFAAM-ZETCQYMHSA-N Water Solubility dilute aqueous acid: soluble |
| Tax Rebate | 13.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Hygiene supervision and inspection of imported food S. Hygiene supervision and inspection of exported food |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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