| Chemical & Physical Properties | |
|---|---|
| CAS Number | 83463-62-1 |
| Catalog No. | 2A-1167608 |
| Chinese Name | 溴代氯乙腈 |
| Synonyms | BROMOCHLOROACETONITRILE; Bromo(chloro)acetonitrile; UNII:SHY3J1BBQ6; 2-bromo-2-chloroacetonitrile |
| Molecular Formula | C2HBrClN |
| Molecular Weight | 154.393 |
| Density | 1.9±0.1 g/cm3 |
| Boiling Point | 121.1±20.0 °C at 760 mmHg |
| Storage Condition | Warehouse ventilation, drying and low temperature |
| Packaging | III |
| Application | Bromochloroacetonitrile is a chlorine disinfection by-product of water containing natural organic matter. Bromochloroacetonitrile has direct mutagenic activity and can induce DNA strand breaks. |
| HTC | 2926909090 |
| PubChem ID | 5413838 |
| SMILES | N#CC(Cl)Br |
| InChI | InChI=1S/C2HBrClN/c3-2(4)1-5/h2H |
| InChI Key | BMWPPNAUMLRKML-UHFFFAOYSA-N |
| Hazard Symbols | 8 |
| Use of | Bromochloroacetonitrile is a by-product of the chlorine disinfection of water containing natural organic material. Bromochloroacetonitrile possesses direct acting mutagenic activity and is capable of inducing DNA strand breakage[1]. Properties Name Bromochloroacetonitrile Synonym More Synonyms UNII:SHY3J1BBQ6 Biological Activity Description Bromochloroacetonitrile is a by-product of the chlorine disinfection of water containing natural organic material. Bromochloroacetonitrile possesses direct acting mutagenic activity and is capable of inducing DNA strand breakage[1]. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Research Areas >> Others In Vitro Bromochloroacetonitrile (BCAN) induces sister chromatid exchange in Chinese hamster ovary cells[1]. References [1]. Suzanne A. et al.The developmental toxicity of bromochloroacetonitrile in pregnant long‐evans rats, International Journal of Environmental Health Research, 5:2, 175-188. Chemical & Physical Properties Molecular Formula C2HBrClN Exact Mass 152.898087 PSA 23.79000 Index of Refraction 1.507 InChIKey BMWPPNAUMLRKML-UHFFFAOYSA-N SMILES N#CC(Cl)Br Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : Acetonitrile, bromochloro- CAS REGISTRY NUMBER : 83463-62-1 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C2-H-Br-Cl-N MOLECULAR WEIGHT : WISWESSER LINE NOTATION : HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SEX/DURATION : female 7-21 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SEX/DURATION : female 6-18 day(s) after conception TOXIC EFFECTS : Reproductive - Maternal Effects - other effects TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SEX/DURATION : female 6-18 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Specific Developmental Abnormalities - musculoskeletal system TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SEX/DURATION : female 6-18 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system TYPE OF TEST : Micronucleus test MUTATION DATA TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 4200 nmol/L REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 5,1065,1985 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,269,1991 IARC Cancer Review:Human No Available Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,269,1991 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,269,1991 Safety Information Hazard Codes Xn RIDADR UN 1760 RTECS AL8010000 Packaging Group III Hazard Class 8 HS Code 2926909090 Synthetic Route Total: 1 Page 2-chloroacetonitrile CAS#:107-14-2 Tribromoacetonitrile CAS#:75519-19-6 UNII:SHY3J1BBQ6 CAS#:83463-62-1 Dibromochloroac... CAS#:144772-39-4 Literature: Water Research, , vol. 33, # 8 p. 1938 - 1948 |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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