![N,N-DIMETHYL-4-(6-METHYLBENZO[D]THIAZOL-2-YL)ANILINE structure, CAS 10205-62-6](/structures/180000/160286_1_10205_62_6.png)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 10205-62-6 |
| Catalog No. | 2A-0160286 |
| Chinese Name | 2-(4'-(二甲基氨基)苯基)-6-甲基-苯并噻唑 |
| Synonyms | 2-<4-Dimethylamino-phenyl>-6-methyl-benzothiazol; MFCD00192069; EINECS 233-506-7 |
| Molecular Formula | C16H16N2S1 |
| Molecular Weight | 268.38 |
| Purity | 96+ |
| Density | 1.188g/cm3 |
| Boiling Point | 428.8ºC at 760mmHg |
| Melting Point | 204-206ºC(lit.) |
| Storage Condition | Seal in a cool, dry place. |
| Application | The benzothiazole dye BTA-2 is structurally similar to thioflavin T (ThT), and its fluorescence signal is enhanced when combined with amyloid fibrils. BTA-2 has distinct absorption and emission proper |
| EINECS | 0 |
| HTC | 2934999090 |
| UN(IATA) | 0 |
| PubChem ID | 5909504 |
| MDL Number | MFCD00192069 |
| SMILES | Cc1ccc2nc(-c3ccc(N(C)C)cc3)sc2c1 |
| InChI | InChI=1S/C16H16N2S/c1-11-4-9-14-15(10-11)19-16(17-14)12-5-7-13(8-6-12)18(2)3/h4-10H,1-3H3 |
| InChI Key | OEOPVJYUCSQVMJ-UHFFFAOYSA-N |
| MSDS | msds/160286_1_10205_62_6.pdf |
| Use of | BTA-2, a benzothiazole dye, is structurally similar to thioflavin T (ThT), which exhibits an enhanced fluorescence signal when bound to amyloid fibrils. BTA-2 has distinct absorption and emission characteristics in solution and when bound to amyloid fibrils, which makes it can used for identifying amyloid fibrils using spectroscopy[1]. Properties Name N,N-dimethyl-4-(6-methyl-1,3-benzothiazol-2-yl)aniline Synonym More Synonyms BTA-2 Biological Activity Description BTA-2, a benzothiazole dye, is structurally similar to thioflavin T (ThT), which exhibits an enhanced fluorescence signal when bound to amyloid fibrils. BTA-2 has distinct absorption and emission characteristics in solution and when bound to amyloid fibrils, which makes it can used for identifying amyloid fibrils using spectroscopy[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Catherine C Kitts, et al. A spectroscopic study of 2-[4'-(dimethylamino)phenyl]-benzothiazole binding to insulin amyloid fibrils. J Fluoresc. 2010 Jul;20(4):881-9. Chemical & Physical Properties Molecular Formula C16H16N2S Exact Mass 268.10300 PSA 44.37000 LogP 4.33770 Index of Refraction 1.669 InChIKey OEOPVJYUCSQVMJ-UHFFFAOYSA-N Safety Information Hazard Codes Xi: Irritant; HS Code 2934999090 Synthetic Route Thioflavine T CAS#:2390-54-7 CAS#:10205-62-6 Literature: Garmaise; Paris; Komlossy; Chambers; McCrae Journal of medicinal chemistry, 1969 , vol. 12, # 1 p. 30 - 36 CAS#:16862-65-0 CAS#:10205-62-6 Literature: Garmaise; Paris; Komlossy; Chambers; McCrae Journal of medicinal chemistry, 1969 , vol. 12, # 1 p. 30 - 36 4-(6-Methyl-2-b... CAS#:92-36-4 methyl iodide CAS#:74-88-4 CAS#:10205-62-6 Precursor & DownStream Precursor 6 CAS#:4755-50-4 4-(Dimethylamin... CAS#:23451-96-9 4-Methylmercapt... CAS#:2390-54-7 Thioflavine T CAS#:67-56-1 DownStream 1 CAS#:2390-54-7 Thioflavine T |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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