CAS Number112-27-6
SynonymsTriglycol; 2,2'-[Ethane-1,2-diylbis(oxy)]diethanol; 2,2'-(Ethane-1,2-diylbis(oxy))diethanol; triethyleneglycol; 1,2-bis(2-hydroxyethoxy)ethane; 2,2'-(Ethylenedioxy)diethanol; Triethylene glycol; 2-[2-(2-hydroxyethoxy)ethoxy]ethanol; 2,2'-[1,2-Ethanediylbis(oxy)]diethanol; TEG; EINECS 203-953-2; MFCD00002880
Molecular FormulaHO(CH2CH2O)2CH2CH2OH
Molecular Weight150.17
Purity99%
Density1.1±0.1 g/cm3
Boiling Point125-127 °C/0.1 mmHg (lit.)
Melting Point−7 °C (lit.)
Appearanceviscous liquid
EINECS203-953-2
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 112-27-6 |
| Catalog No. | 2A-9016024 |
| Chinese Name | 三甘醇 |
| Synonyms | Triglycol; 2,2'-[Ethane-1,2-diylbis(oxy)]diethanol; 2,2'-(Ethane-1,2-diylbis(oxy))diethanol; triethyleneglycol; 1,2-bis(2-hydroxyethoxy)ethane; 2,2'-(Ethylenedioxy)diethanol; Triethylene glycol; 2-[2-(2-hydroxyethoxy)ethoxy]ethanol; 2,2'-[1,2-Ethanediylbis(oxy)]diethanol; TEG; EINECS 203-953-2; MFCD00002880 |
| Molecular Formula | HO(CH2CH2O)2CH2CH2OH |
| Molecular Weight | 150.17 |
| Purity | 99 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 125-127 °C/0.1 mmHg (lit.) |
| Melting Point | −7 °C (lit.) |
| Appearance | viscous liquid |
| Water Solubility | SOLUBLE |
| Storage Condition | 1. Store in a cool, ventilated warehouse. Keep awa |
| Application | PROTAC Linker 25 is a PEG-type PROTAC link bridge. PROTAC Linker 25 can be used to synthesize a range of PROTAC molecules. PROTAC molecules contain two different ligands connected by a linking bridge; |
| EINECS | 203-953-2 |
| HTC | 2905399090 |
| PubChem ID | 24900333 |
| MDL Number | MFCD00002880 |
| SMILES | OCCOCCOCCO |
| InChI | 1S/C6H14O4/c7-1-3-9-5-6-10-4-2-8/h7-8H,1-6H2 |
| InChI Key | ZIBGPFATKBEMQZ-UHFFFAOYSA-N |
| Beilstein/REAXYS | 969357 |
| NACRES Code | NA.21 |
| UNSPSC | 12352100 |
| Hazard Symbols | Transport |
| MSDS | msds/16024_1_112_27_6.pdf |
| Bioactivity | PROTAC Linker 25 is a polyethylene glycol (PEG)-based PROTAC linker. PROTAC Linker 25 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target PEGs References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 288.0±0.0 °C at 760 mmHg Melting Point −7 °C(lit.) Molecular Formula C6H14O4 Molecular Weight 150.173 Flash Point 165.6±0.0 °C Exact Mass 150.089203 PSA 58.92000 LogP -1.87 Vapour density 5.2 (vs air) Vapour Pressure 0.0±1.3 mmHg at 25°C Index of Refraction 1.451 InChIKey ZIBGPFATKBEMQZ-UHFFFAOYSA-N SMILES OCCOCCOCCO Stability Stable. Combustible. Incompatible with strong oxidizing agents. Water Solubility SOLUBLE |
| Use of | Properties Name triethylene glycol Synonym More Synonyms Triethylene glycol Biological Activity Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. Chemical & Physical Properties Molecular Formula C6H14O4 Exact Mass 150.089203 PSA 58.92000 LogP -1.87 Vapour density 5.2 (vs air) Index of Refraction 1.451 InChIKey ZIBGPFATKBEMQZ-UHFFFAOYSA-N SMILES OCCOCCOCCO Stability Stable. Combustible. Incompatible with strong oxidizing agents. Water Solubility SOLUBLE |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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