
CAS Number50912-92-0
SynonymsMethyl (E)-N-[amino(nitroamino)methylene]-D-ornithinate hydrochloride (1:1); methyl (2S)-2-amino-5-{[imino(nitroamino)methyl]amino}pentanoate,chloride; MFCD00133613; NG-nitro-L-Arg-OMe*HCl; NG-Nitro-D-arginine methyl ester hydrochloride; H-Arg(NO2)-OMe.HCl; L-NAME (hydrochloride); D-Ornithine, N-[amino(nitroamino)methylene]-, methyl ester, (E)-, hydrochloride (1:1); D-NAME NG-Nitro-D-arginine methyl ester hydrochloride; N5-[Imino(nitroamino)methyl]-D-ornithine methyl ester hydrochloride; H-D-Arg(NO2)-OMe HCl; H-D-Arg(NO2)-Ome.HCl
Molecular FormulaC7H16ClN5O4
Molecular Weight269.69
Purity96+%
Boiling Point410.7ºC at 760 mmHg
Melting Point150-160 °C
EINECS0
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 50912-92-0 |
| Catalog No. | 2A-0156003 |
| Chinese Name | NG-硝基-D-精氨酸甲基酯盐酸盐 |
| Synonyms | Methyl (E)-N-[amino(nitroamino)methylene]-D-ornithinate hydrochloride (1:1); methyl (2S)-2-amino-5-{[imino(nitroamino)methyl]amino}pentanoate,chloride; MFCD00133613; NG-nitro-L-Arg-OMe*HCl; NG-Nitro-D-arginine methyl ester hydrochloride; H-Arg(NO2)-OMe.HCl; L-NAME (hydrochloride); D-Ornithine, N-[amino(nitroamino)methylene]-, methyl ester, (E)-, hydrochloride (1:1); D-NAME NG-Nitro-D-arginine methyl ester hydrochloride; N5-[Imino(nitroamino)methyl]-D-ornithine methyl ester hydrochloride; H-D-Arg(NO2)-OMe HCl; H-D-Arg(NO2)-Ome.HCl |
| Molecular Formula | C7H16ClN5O4 |
| Molecular Weight | 269.69 |
| Purity | 96+ |
| Boiling Point | 410.7ºC at 760 mmHg |
| Melting Point | 150-160 °C |
| Storage Condition | Sealed, store at -20 ºC |
| Application | D-NAME hydrochloride (D-NG-nitroarginine methyl ester) is a potent nitric oxide synthase (NOS) inhibitor. D-NAME hydrochloride inhibits the activity of NOS and reduces the production of nitric oxide. |
| EINECS | 0 |
| HTC | 2925290090 |
| UN(IATA) | 0 |
| PubChem ID | 3153172 |
| SMILES | COC(=O)C(N)CCCN=C(N)N[N+](=O)[O-].Cl |
| InChI | InChI=1S/C7H15N5O4.ClH/c1-16-6(13)5(8)3-2-4-10-7(9)11-12(14)15;/h5H,2-4,8H2,1H3,(H3,9,10,11);1H/t5-;/m1./s1 |
| InChI Key | QBNXAGZYLSRPJK-NUBCRITNSA-N |
| Hazard Symbols | transportation |
| Bioactivity | D-NAME (D-NG-nitroarginine methyl ester) hydrochloride is a potent nitric oxide synthase (NOS) inhibitor. D-NAME hydrochloride inhibits the activity of NOS, reducing the production of nitric oxide[1]. Related Catalog Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Neurological Disease References [1]. Palmer RM, et, al. L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation. Biochem Biophys Res Commun. 1988 Jun 30;153(3):1251-6. Chemical & Physical Properties Boiling Point 410.7ºC at 760 mmHg Melting Point 150-160 °C Molecular Formula C7H16ClN5O4 Molecular Weight 269.69 Flash Point 202.2ºC Exact Mass 269.089081 PSA 146.05000 LogP 1.47960 InChIKey QBNXAGZYLSRPJK-NUBCRITNSA-N SMILES COC(=O)C(N)CCCN=C(N)N[N+](=O)[O-].Cl Storage condition −20°C |
| Use of | D-NAME (D-NG-nitroarginine methyl ester) hydrochloride is a potent nitric oxide synthase (NOS) inhibitor. D-NAME hydrochloride inhibits the activity of NOS, reducing the production of nitric oxide[1]. Properties Name methyl 2-amino-5-[[amino(nitramido)methylidene]amino]pentanoate,hydrochloride Synonym More Synonyms H-D-Arg(NO2)-Ome.HCl Biological Activity Description D-NAME (D-NG-nitroarginine methyl ester) hydrochloride is a potent nitric oxide synthase (NOS) inhibitor. D-NAME hydrochloride inhibits the activity of NOS, reducing the production of nitric oxide[1]. Related Catalog Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Neurological Disease References [1]. Palmer RM, et, al. L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation. Biochem Biophys Res Commun. 1988 Jun 30;153(3):1251-6. Chemical & Physical Properties Exact Mass 269.089081 PSA 146.05000 LogP 1.47960 InChIKey QBNXAGZYLSRPJK-NUBCRITNSA-N SMILES COC(=O)C(N)CCCN=C(N)N[N+](=O)[O-].Cl |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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