![6A,7,8,9-TETRAHYDRO-2H-[1,4]DIOXINO[2',3':4,5]BENZO[1,2-E]PYRROLO[2,1-B][1,3]OXAZIN-11(3H)-ONE structure, CAS 191744-13-5](/structures/150000/148892_3_191744_13_5.png)
CAS Number191744-13-5
SynonymsCX 614; BDP 37; 2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one; 6a,7,8,9-Tetrahydro-2H-[1,4]dioxino[2',3':4,5]benzo[1,2-e]pyrrolo[2,1-b][1,3]oxazin-11(3H)-one; LiD 37; CX-614
Molecular FormulaC13H13NO4
Molecular Weight247.24700
Purity96+%
Density1.45g/cm3
Boiling Point473.8ºC at 760 mmHg
EINECS0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 191744-13-5 |
| Catalog No. | 2A-0148892 |
| Chinese Name | 2,3,6a,7,8,9-六氢-11H-1,4-二恶烷并[2,3-g]吡咯并[2,1-b][1,3]苯并恶嗪-11-酮 |
| Synonyms | CX 614; BDP 37; 2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one; 6a,7,8,9-Tetrahydro-2H-[1,4]dioxino[2',3':4,5]benzo[1,2-e]pyrrolo[2,1-b][1,3]oxazin-11(3H)-one; LiD 37; CX-614 |
| Molecular Formula | C13H13NO4 |
| Molecular Weight | 247.24700 |
| Purity | 96+ |
| Density | 1.45g/cm3 |
| Boiling Point | 473.8ºC at 760 mmHg |
| Storage Condition | 2-8°C |
| Application | CX614 is a positive variant modulator of AMPA receptors that enhances excitatory postsynaptic potentials (amplitude and duration) by blocking and slowing inactivation of glutamate responses and automa |
| EINECS | 0 |
| HTC | 2934999090 |
| UN(IATA) | 0 |
| SMILES | O=C1c2cc3c(cc2OC2CCCN12)OCCO3 |
| InChI | InChI=1S/C13H13NO4/c15-13-8-6-10-11(17-5-4-16-10)7-9(8)18-12-2-1-3-14(12)13/h6-7,12H,1-5H2 |
| InChI Key | RQEPVMAYUINZRE-UHFFFAOYSA-N |
| Use of | Properties Name cx614 Synonym More Synonyms CX 614 Biological Activity Related Catalog Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR References [1]. Wei Dai, et al. The Impact and Mechanism of a Novel Allosteric AMPA Receptor Modulator LCX001 on Protection Against Respiratory Depression in Rodents. Front Pharmacol. 2019 Feb 19;10:105. [2]. Eleni Dicou, et al. Positive allosteric modulators of AMPA receptors are neuroprotective against lesions induced by an NMDA agonist in neonatal mouse brain. Brain Res. 2003 Apr 25;970(1-2):221-5. Chemical & Physical Properties Molecular Formula C13H13NO4 Exact Mass 247.08400 PSA 48.00000 LogP 1.35020 Index of Refraction 1.651 InChIKey RQEPVMAYUINZRE-UHFFFAOYSA-N Safety Information HS Code 2934999090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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