CAS Number4321-58-8
Synonyms6-Aminohexanoic acid hydrochloride (1:1); 6-Aminohexanoic acid hydrochloride; Hexanoic acid, 6-amino-, hydrochloride (1:1); 6-aminohexanoic acid,hydrochloride; Hexanoic acid, 6-amino-, hydrochloride; ε-Aminocaproic acid hydrochloride; AMINOCAPROIC ACID HYDROCHLORIDE
Molecular FormulaC6H14O2N1Cl1
Molecular Weight167.64
Purity96+%
EINECS0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 4321-58-8 |
| Catalog No. | 2A-0146787 |
| Chinese Name | 6-氨基己酸盐酸盐 |
| Synonyms | 6-Aminohexanoic acid hydrochloride (1:1); 6-Aminohexanoic acid hydrochloride; Hexanoic acid, 6-amino-, hydrochloride (1:1); 6-aminohexanoic acid,hydrochloride; Hexanoic acid, 6-amino-, hydrochloride; ε-Aminocaproic acid hydrochloride; AMINOCAPROIC ACID HYDROCHLORIDE |
| Molecular Formula | C6H14O2N1Cl1 |
| Molecular Weight | 167.64 |
| Purity | 96+ |
| Storage Condition | Room temperature, sealed, dry |
| Application | 6-Aminocaproic acid hydrochloride is a monoaminocarboxylic acid and a potent orally active plasmin and plasminogen inhibitor. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic aci |
| EINECS | 0 |
| HTC | 2923900090 |
| UN(IATA) | 0 |
| MDL Number | MFCD16251184 |
| SMILES | Cl.NCCCCCC(=O)O |
| InChI Key | AENOKLOQCCSDAZ-UHFFFAOYSA-N |
| MSDS | msds/146787_1_4321_58_8.pdf |
| Use of | 6-Aminocaproic acid hydrochloride, a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders[1][2]. Properties Name 6-Aminohexanoic acid hydrochloride Synonym More Synonyms AMINOCAPROIC ACID HYDROCHLORIDE Biological Activity Description 6-Aminocaproic acid hydrochloride, a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders[1][2]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease In Vitro 6-Aminocaproic acid hydrochloride (20-180 μg/mL) inhibits fibrinolysis in plasma of Asian elephants, with an effective concentration of 61.5 μg/mL[2]. 6-Aminocaproic acid hydrochloride can be used as a hydrophobic linker to improve near-infrared fluorescence imaging and photothermal cancer therapy of PEGylated indocyanine green[4]. References [1]. Griffin JD, et, al. Epsilon-aminocaproic acid (EACA). Semin Thromb Hemost. Summer 1978;5(1):27-40. [2]. Kaye S, et, al. EFFECT OF ε-AMINOCAPROIC ACID ON FIBRINOLYSIS IN PLASMA OF ASIAN ELEPHANTS (ELEPHAS MAXIMUS). J Zoo Wildl Med. 2016 Jun;47(2):397-404. [3]. Brown JC, et, al. Effect of aminocaproic acid on clot strength and clot lysis of canine blood determined by use of an in vitro model of hyperfibrinolysis. Am J Vet Res. 2016 Nov;77(11):1258-1265. [4]. Hu Q, et al. 6-Aminocaproic acid as a linker to improve near-infrared fluorescence imaging and photothermal cancer therapy of PEGylated indocyanine green. Colloids Surf B Biointerfaces. 2021 Jan;197:111372. Chemical & Physical Properties Exact Mass 167.071304 PSA 63.32000 LogP 2.09240 InChIKey AENOKLOQCCSDAZ-UHFFFAOYSA-N SMILES Cl.NCCCCCC(=O)O Safety Information HS Code 2923900090 Synthetic Route 6-methoxycarbon... CAS#:70288-80-1 AMINOCAPROIC AC... CAS#:4321-58-8 Literature: Effenberger, Franz; Drauz, Karlheinz; Foerster, Siegfried; Mueller, Wolfgang Chemische Berichte, 1981 , vol. 114, # 1 p. 173 - 189 ethyl 6-(ethoxy... CAS#:5180-73-4 AMINOCAPROIC AC... CAS#:4321-58-8 Literature: Effenberger, Franz; Drauz, Karlheinz; Foerster, Siegfried; Mueller, Wolfgang Chemische Berichte, 1981 , vol. 114, # 1 p. 173 - 189 Caprolactam CAS#:105-60-2 AMINOCAPROIC AC... CAS#:4321-58-8 Literature: The Procter and Gamble Company Patent: US5520835 A1, 1996 ; Precursor & DownStream Precursor 6 CAS#:70288-80-1 6-methoxycarbon... CAS#:5180-73-4 ethyl 6-(ethoxy... CAS#:105-60-2 Caprolactam CAS#:14273-90-6 Methyl 6-bromoh... DownStream 6 CAS#:372-52-1 epsilon-Aminoca... CAS#:66678-88-4 6-Aminohexanoyl... CAS#:4649-06-3 6-(4-oxo-2-sulf... CAS#:61635-28-7 6-(methylsulfan... |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product Name: Summary 2923900090 other quaternary ammonium salts and hydroxides. Supervision conditions:None. VAT: 17.0%. Tax rebate rate:9.0%. MFN tariff: 6.5%. General tariff:30.0% |
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