CAS Number226907-52-4
Synonyms9-Benzyl-8-hydroxy-2-(2-methoxyethoxy)adenine; 6-Amino-9-benzyl-2-(2-methoxyethoxy)-7,9-dihydro-8H-purin-8-one; 6-Amino-9-benzyl-2-(2-methoxyethoxy)-9H-purin-8-ol
Molecular FormulaC15H17O3N5
Molecular Weight315.33
Purity96+%
Density1.4±0.1 g/cm3
Boiling Point626.4±65.0 °C at 760 mmHg
EINECS0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 226907-52-4 |
| Catalog No. | 2A-0146775 |
| Chinese Name | 6-氨基-7,9-二氢-2-(2-甲氧基乙氧基)-9-(苯甲基)-8H-嘌呤-8-酮 |
| Synonyms | 9-Benzyl-8-hydroxy-2-(2-methoxyethoxy)adenine; 6-Amino-9-benzyl-2-(2-methoxyethoxy)-7,9-dihydro-8H-purin-8-one; 6-Amino-9-benzyl-2-(2-methoxyethoxy)-9H-purin-8-ol |
| Molecular Formula | C15H17O3N5 |
| Molecular Weight | 315.33 |
| Purity | 96+ |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 626.4±65.0 °C at 760 mmHg |
| Storage Condition | -20°C, sealed, dry |
| Application | SM-360320 (CL-087) is an orally available TLR7 agonist. SM-360320 is an immunomodulator with anti-tumor effects. SM-360320 can synergize with DNA vaccines to enhance Th1 antibody responses [1]. In add |
| EINECS | 0 |
| HTC | 2933990090 |
| UN(IATA) | 0 |
| MDL Number | MFCD21337856 |
| SMILES | COCCOc1nc(N)c2[nH]c(=O)n(Cc3ccccc3)c2n1 |
| InChI Key | YYCDGEZXHXHLGW-UHFFFAOYSA-N |
| MSDS | msds/146775_1_226907_52_4.pdf |
| Use of | Properties Name 6-amino-9-benzyl-2-(2-methoxyethoxy)-7H-purin-8-one Synonym More Synonyms Biological Activity Related Catalog Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Inflammation/Immunology References [1]. Dharmapuri S, et al. An oral TLR7 agonist is a potent adjuvant of DNA vaccination in transgenic mouse tumor models. Cancer Gene Ther. 2009;16(5):462-472. [2]. Lee J, et al. Activation of anti-hepatitis C virus responses via Toll-like receptor 7. Proc Natl Acad Sci U S A. 2006;103(6):1828-1833. Chemical & Physical Properties Molecular Formula C15H17N5O3 Exact Mass 315.133148 PSA 108.31000 Index of Refraction 1.675 InChIKey YYCDGEZXHXHLGW-UHFFFAOYSA-N Safety Information HS Code 2933990090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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