CAS Number1477-50-5
Synonyms1H-Indole-2-carboxylic acid; T56 BMJ CVQ; Indole-2-carboxylic acid; 2-Carboxyindole; 2-Indolecarboxylic acid; MFCD00005611; EINECS 216-030-4
Molecular FormulaC9H7NO2
Molecular Weight161.16
Purity98%
Density1.4±0.1 g/cm3
Boiling Point419.6±18.0 °C at 760 mmHg
Melting Point202-206 °C (lit.)
AppearanceOff-white crystal powder
EINECS216-030-4
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1477-50-5 |
| Catalog No. | 2A-9014618 |
| Chinese Name | 吲哚-2-羧酸 |
| Synonyms | 1H-Indole-2-carboxylic acid; T56 BMJ CVQ; Indole-2-carboxylic acid; 2-Carboxyindole; 2-Indolecarboxylic acid; MFCD00005611; EINECS 216-030-4 |
| Molecular Formula | C9H7NO2 |
| Molecular Weight | 161.16 |
| Purity | 98 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 419.6±18.0 °C at 760 mmHg |
| Melting Point | 202-206 °C (lit.) |
| Appearance | Off-white crystal powder |
| Storage Condition | Keep the receptacle sealed, stored in a cool, dry |
| Application | Indole-2-carboxylic acid is a potent inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiating effect of glycine on NMDA-gated currents. |
| EINECS | 216-030-4 |
| HTC | 29339990 |
| PubChem ID | 24895981 |
| MDL Number | MFCD00005611 |
| SMILES | OC(=O)c1cc2ccccc2[nH]1 |
| InChI | 1S/C9H7NO2/c11-9(12)8-5-6-3-1-2-4-7(6)10-8/h1-5,10H,(H,11,12) |
| InChI Key | HCUARRIEZVDMPT-UHFFFAOYSA-N |
| Beilstein/REAXYS | 124132 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | Transport |
| MSDS | msds/14618_1_1477_50_5.pdf |
| Bioactivity | Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2]. Related Catalog Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR Target Human Endogenous Metabolite References [1]. 2-Indolecarboxylic acid. [2]. J E Huettner, et al. Indole-2-carboxylic Acid: A Competitive Antagonist of Potentiation by Glycine at the NMDA Receptor. Science. 1989 Mar 24;243(4898):1611-3. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 419.6±18.0 °C at 760 mmHg Melting Point 202-206 °C(lit.) Molecular Formula C9H7NO2 Molecular Weight 161.157 Flash Point 207.6±21.2 °C Exact Mass 161.047684 PSA 53.09000 LogP 2.31 Vapour Pressure 0.0±1.0 mmHg at 25°C Index of Refraction 1.726 InChIKey HCUARRIEZVDMPT-UHFFFAOYSA-N SMILES O=C(O)c1cc2ccccc2[nH]1 |
| Use of | Properties Articles26 Name Indole-2-carboxylic acid Synonym More Synonyms Indole-2-carboxylic acid Biological Activity Related Catalog Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR Human Endogenous Metabolite References [1]. 2-Indolecarboxylic acid. [2]. J E Huettner, et al. Indole-2-carboxylic Acid: A Competitive Antagonist of Potentiation by Glycine at the NMDA Receptor. Science. 1989 Mar 24;243(4898):1611-3. Chemical & Physical Properties Molecular Formula C9H7NO2 Exact Mass 161.047684 PSA 53.09000 Index of Refraction 1.726 InChIKey HCUARRIEZVDMPT-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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