CAS Number288-32-4
SynonymsIMD; 1,3-Diaza-2,4-cyclopentadiene,Glyoxaline; GLYOXALIN; LMIDAZOLE; glioksal; 1,3-diaza-2,4-cyclopentadiene; Imidazol; Miazole; 1,3-imidazole; Imidazoie; Imidazole; MFCD00005183; 1-imidazole; EINECS 206-019-2; Imidazole buffer; IMINAZOLE; 1,3-diazole; Imutex
Molecular FormulaC3H4N2
Molecular Weight68.08
Purity99%
Density1.1±0.1 g/cm3
Boiling Point256 °C (lit.)
Melting Point88-91 °C (lit.)
Appearancecrystalline
EINECS206-019-2
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 288-32-4 |
| Catalog No. | 2A-9014596 |
| Chinese Name | 咪唑 |
| Synonyms | IMD; 1,3-Diaza-2,4-cyclopentadiene,Glyoxaline; GLYOXALIN; LMIDAZOLE; glioksal; 1,3-diaza-2,4-cyclopentadiene; Imidazol; Miazole; 1,3-imidazole; Imidazoie; Imidazole; MFCD00005183; 1-imidazole; EINECS 206-019-2; Imidazole buffer; IMINAZOLE; 1,3-diazole; Imutex |
| Molecular Formula | C3H4N2 |
| Molecular Weight | 68.08 |
| Purity | 99 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 256 °C (lit.) |
| Melting Point | 88-91 °C (lit.) |
| Appearance | crystalline |
| Water Solubility | 633 g/L (20 ºC) |
| Storage Condition | Packed in wooden barrels or glass bottles. Store i |
| Packaging | III |
| Application | Imidazole is a planar five-membered ring and a highly polar compound that has been widely used as a corrosion inhibitor |
| EINECS | 206-019-2 |
| HTC | 2933990090 |
| PubChem ID | 329815362 |
| MDL Number | MFCD00005183 |
| SMILES | c1c[nH]cn1 |
| InChI | 1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5) |
| InChI Key | RAXXELZNTBOGNW-UHFFFAOYSA-N |
| Beilstein/REAXYS | 103853 |
| NACRES Code | NA.25 |
| eCl@ss | 39161001 |
| UNSPSC | 12352005 |
| Hazard Symbols | 8 |
| MSDS | msds/14596_1_288_32_4.pdf |
| Bioactivity | Imidazole is a planar 5-membered ring. Imidazole is a highly polar compound. Imidazole has been used extensively as a corrosion inhibitor.Imidazole is incorporated into many important biological molecules. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Imidazole is useful as a buffer in the pH range of 6.2-7.8 One of the applications of imidazole is in the purification of His-tagged proteins in immobilised metal affinity chromatography(IMAC). Imidazole is used to elute tagged proteins bound to Ni ions attached to the surface of beads in the chromatography column. An excess of imidazole is passed through the column, which displaces the His-tag from nickel co-ordination, freeing the His-tagged proteins. Imidazole has become an important part of many pharmaceuticals. Synthetic imidazoles are present in many fungicides and antifungal, antiprotozoal, and antihypertensive medications. Imidazole is part of the theophylline molecule, found in tea leaves and coffee beans, which stimulates the central nervous system. It is present in the anticancer medication mercaptopurine, which combats leukemia by interfering with DNA activities. Related Catalog Signaling Pathways >> Others >> Others Biochemical Assay Reagents Research Areas >> Others Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 257.0±9.0 °C at 760 mmHg Melting Point 88-91 °C(lit.) Molecular Formula C3H4N2 Molecular Weight 68.077 Flash Point 145.0±0.0 °C Exact Mass 68.037445 PSA 28.68000 LogP -0.16 Vapour Pressure 0.0±0.5 mmHg at 25°C Index of Refraction 1.528 InChIKey RAXXELZNTBOGNW-UHFFFAOYSA-N SMILES c1c[nH]cn1 Storage condition 2-8°C Stability Stable. Incompatible with acids, strong oxidizing agents. Protect from moisture. Water Solubility 633 g/L (20 ºC) |
| Use of | Imidazole is a planar 5-membered ring. Imidazole is a highly polar compound. Imidazole has been used extensively as a corrosion inhibitor.Imidazole is incorporated into many important biological molecules. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Imidazole is useful as a buffer in the pH range of 6.2-7.8 One of the applications of imidazole is in the purification of His-tagged proteins in immobilised metal affinity chromatography(IMAC). Imidazole is used to elute tagged proteins bound to Ni ions attached to the surface of beads in the chromatography column. An excess of imidazole is passed through the column, which displaces the His-tag from nickel co-ordination, freeing the His-tagged proteins. Imidazole has become an important part of many pharmaceuticals. Synthetic imidazoles are present in many fungicides and antifungal, antiprotozoal, and antihypertensive medications. Imidazole is part of the theophylline molecule, found in tea leaves and coffee beans, which stimulates the central nervous system. It is present in the anticancer medication mercaptopurine, which combats leukemia by interfering with DNA activities. Properties Articles817 Name 1H-imidazole Synonym More Synonyms Imidazole Biological Activity Description Imidazole is a planar 5-membered ring. Imidazole is a highly polar compound. Imidazole has been used extensively as a corrosion inhibitor.Imidazole is incorporated into many important biological molecules. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Imidazole is useful as a buffer in the pH range of 6.2-7.8 One of the applications of imidazole is in the purification of His-tagged proteins in immobilised metal affinity chromatography(IMAC). Imidazole is used to elute tagged proteins bound to Ni ions attached to the surface of beads in the chromatography column. An excess of imidazole is passed through the column, which displaces the His-tag from nickel co-ordination, freeing the His-tagged proteins. Imidazole has become an important part of many pharmaceuticals. Synthetic imidazoles are present in many fungicides and antifungal, antiprotozoal, and antihypertensive medications. Imidazole is part of the theophylline molecule, found in tea leaves and coffee beans, which stimulates the central nervous system. It is present in the anticancer medication mercaptopurine, which combats leukemia by interfering with DNA activities. Related Catalog Signaling Pathways >> Others >> Others Biochemical Assay Reagents Research Areas >> Others Chemical & Physical Properties Molecular Formula C3H4N2 Exact Mass 68.037445 PSA 28.68000 LogP -0.16 Index of Refraction 1.528 InChIKey RAXXELZNTBOGNW-UHFFFAOYSA-N Stability Stable. Incompatible with acids, strong oxidizing agents. Protect from moisture. |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Danger Regulations: 3263 International Maritime Danger Regulations: 3263 International Air Transport Danger Regulations: 3263 14.2 United Nations shipping name European Land Transport Dangerous Regulations: CORROSIVE SOLID, BASIC, ORGANIC, N.O.S. (Imidazole) IMDG Code: CORROSIVE SOLID, BASIC, ORGANIC, N.O.S. (Imidazole) International Air Transport Regulations: Corrosive solid, basic, organic, n.o.s. (Imidazole) 14.3 Transport hazard categories European Dangerous Regulations for land transport: 8 International Dangerous Regulations for sea transport: 8 International Dangerous Regulations for air transport: 8 14.4 Package group European Dangerous Regulations for land transport: II International Dangerous Regulations for sea transport: II International Dangerous Regulations for air transport: II 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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