CAS Number110-94-1
SynonymsIressa; Pentanedioic acid; Irressat; 1,5-Pentanedioate; Propane-1,3-dicarboxylic acid; n-Pyrotartaric acid; 1,5-Pentanedioic acid; 1,3-propanedicarboxylic acid; EINECS 203-817-2; hydrogen glutarate; Glutaric acid; ZD 1839; Gefitinib; 1,3-Propanedicarboxylate; MFCD00004410
Molecular FormulaHOOC(CH2)3COOH
Molecular Weight132.11
Purity99%
Density1.3±0.1 g/cm3
Boiling Point200 °C/20 mmHg (lit.)
Melting Point95-98 °C (lit.)
Appearanceclear liquid
EINECS203-817-2
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 110-94-1 |
| Catalog No. | 2A-9014518 |
| Chinese Name | 戊二酸 |
| Synonyms | Iressa; Pentanedioic acid; Irressat; 1,5-Pentanedioate; Propane-1,3-dicarboxylic acid; n-Pyrotartaric acid; 1,5-Pentanedioic acid; 1,3-propanedicarboxylic acid; EINECS 203-817-2; hydrogen glutarate; Glutaric acid; ZD 1839; Gefitinib; 1,3-Propanedicarboxylate; MFCD00004410 |
| Molecular Formula | HOOC(CH2)3COOH |
| Molecular Weight | 132.11 |
| Purity | 99 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 200 °C/20 mmHg (lit.) |
| Melting Point | 95-98 °C (lit.) |
| Appearance | clear liquid |
| Water Solubility | 430 g/L (20 ºC) |
| Storage Condition | 1. Store in a cool, ventilated warehouse. Keep awa |
| Application | Glutaric acid induces oxidative stress in the brain of young rats. |
| EINECS | 203-817-2 |
| HTC | 2932999099 |
| PubChem ID | 24895125 |
| MDL Number | MFCD00004410 |
| SMILES | OC(=O)CCCC(O)=O |
| InChI | 1S/C5H8O4/c6-4(7)2-1-3-5(8)9/h1-3H2,(H,6,7)(H,8,9) |
| InChI Key | JFCQEDHGNNZCLN-UHFFFAOYSA-N |
| Beilstein/REAXYS | 1209725 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| MSDS | msds/14518_1_110_94_1.pdf |
| Bioactivity | Glutaric acid induces oxidative stress in brain of young rats. Related Catalog Natural Products >> Acids and Aldehydes Research Areas >> Metabolic Disease Target Human Endogenous Metabolite In Vitro Glutaric acid (GA) at concentrations of 1 and 2 mM is able to reduce TRAP measurement by up to 28% in a dose-dependent manner (β=0.77; P<0.001). Furthermore, a significantly inverse correlation is also verified between chemiluminescence and TRAP (β=0.81; P<0.001). Glutaric acid does not alter the activities of Cat and SOD, but strongly inhibits (up to 46%) the activity of GPx even at the lower concentration used (0.5 mM). It is observed that the metabolite inhibits this activity in a dose-dependent manner at concentrations as low as 0.05 mM[1]. References [1]. de Oliveira Marques F, et al. acid induces oxidative stress in brain of young rats. Brain Res. 2003 Feb 21;964(1):153-8. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 302.9±15.0 °C at 760 mmHg Melting Point 95-98 °C(lit.) Molecular Formula C5H8O4 Molecular Weight 132.115 Flash Point 151.2±16.9 °C Exact Mass 132.042252 PSA 74.60000 LogP -1.04 Vapour Pressure 0.0±1.4 mmHg at 25°C Index of Refraction 1.477 InChIKey JFCQEDHGNNZCLN-UHFFFAOYSA-N SMILES O=C(O)CCCC(=O)O Storage condition 2-8°C Stability Stable. Incompatible with bases, oxidizing agents, reducing agents. Water Solubility 430 g/L (20 ºC) |
| Use of | Glutaric acid induces oxidative stress in brain of young rats. Properties Articles59 Name glutaric acid Synonym More Synonyms Glutaric acid Biological Activity Description Glutaric acid induces oxidative stress in brain of young rats. Related Catalog Natural Products >> Acids and Aldehydes Research Areas >> Metabolic Disease Human Endogenous Metabolite References [1]. de Oliveira Marques F, et al. acid induces oxidative stress in brain of young rats. Brain Res. 2003 Feb 21;964(1):153-8. Chemical & Physical Properties Molecular Formula C5H8O4 Exact Mass 132.042252 PSA 74.60000 LogP -1.04 Index of Refraction 1.477 InChIKey JFCQEDHGNNZCLN-UHFFFAOYSA-N SMILES O=C(O)CCCC(=O)O Stability Stable. Incompatible with bases, oxidizing agents, reducing agents. |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Chemical name |
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