CAS Number1401-69-0
SynonymsEINECS 215-754-8; Tylan 100; Vetil(R); Vetil; tylocine; TYLOCINE(R); Tylosine; TYLAN50; fradizine; Tylon; Tylosin,predominantly Tylosin A; TYLOSIN
Molecular FormulaC46H77NO17
Molecular Weight916.10
Purity98.00%
Density1.2±0.1 g/cm3
Boiling Point980.7±65.0 °C at 760 mmHg
Melting Point18-132ºC
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1401-69-0 |
| Catalog No. | 2A-9012879 |
| Chinese Name | 泰乐菌素 |
| Synonyms | EINECS 215-754-8; Tylan 100; Vetil(R); Vetil; tylocine; TYLOCINE(R); Tylosine; TYLAN50; fradizine; Tylon; Tylosin,predominantly Tylosin A; TYLOSIN |
| Molecular Formula | C46H77NO17 |
| Molecular Weight | 916.10 |
| Purity | 98.00 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 980.7±65.0 °C at 760 mmHg |
| Melting Point | 18-132ºC |
| Storage Condition | Sealed, stored at 2ºC -8ºC |
| Application | Tylosin (Fradizine; Tylocine; Tylosin A) is a broad-spectrum Gram-positive antibiotic that is also effective against some Gram-negative bacteria. |
| MDL Number | MFCD09753818 |
| SMILES | CCC1OC(=O)CC(O)C(C)C(OC2OC(C)C(OC3CC(C)(O)C(O)C(C)O3)C(N(C)C)C2O)C(CC=O)CC(C)C(=O)C=CC(C)=CC1COC1OC(C)C(O)C(OC)C1OC |
| InChI | 1S/C46H77NO17/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3/b15-14+,23-18+/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-/m1/s1 |
| InChI Key | WBPYTXDJUQJLPQ-VMXQISHHSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/12879_1_1401_69_0.pdf |
| Bioactivity | Tylosin (Fradizine; Tylocine; Tylosin A) is a broad spectrum antibiotic against Gram-positive organisms and a limited range of Gram-negative organisms. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Natural Products >> Others Research Areas >> Infection References [1]. Entorf M, et al. Tylosin susceptibility of staphylococci from bovine mastitis. Vet Microbiol. 2014 Jul 16;171(3-4):368-73. [2]. Pilcher CM, et al. Impact of tylosin phosphate and distillers dried grains with solubles on energy and nutrient digestibility and flow through the gastrointestinal tract in growing pigs. J Anim Sci. 2013 Dec;91(12):5687-95. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 980.7±65.0 °C at 760 mmHg Melting Point 18-132ºC Molecular Formula C46H77NO17 Molecular Weight 916.100 Flash Point 546.9±34.3 °C Exact Mass 915.519165 PSA 238.67000 LogP 3.27 Vapour Pressure 0.0±0.6 mmHg at 25°C Index of Refraction 1.549 InChIKey WBPYTXDJUQJLPQ-GSDFIKGFSA-N SMILES CCC1OC(=O)CC(O)C(C)C(OC2OC(C)C(OC3CC(C)(O)C(O)C(C)O3)C(N(C)C)C2O)C(CC=O)CC(C)C(=O)C=CC(C)=CC1COC1OC(C)C(O)C(OC)C1OC Storage condition 2-8°C |
| Use of | Tylosin (Fradizine; Tylocine; Tylosin A) is a broad spectrum antibiotic against Gram-positive organisms and a limited range of Gram-negative organisms. Properties Articles25 Name tylosin Synonym More Synonyms Tylosin Biological Activity Description Tylosin (Fradizine; Tylocine; Tylosin A) is a broad spectrum antibiotic against Gram-positive organisms and a limited range of Gram-negative organisms. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Natural Products >> Others Research Areas >> Infection References [1]. Entorf M, et al. Tylosin susceptibility of staphylococci from bovine mastitis. Vet Microbiol. 2014 Jul 16;171(3-4):368-73. [2]. Pilcher CM, et al. Impact of tylosin phosphate and distillers dried grains with solubles on energy and nutrient digestibility and flow through the gastrointestinal tract in growing pigs. J Anim Sci. 2013 Dec;91(12):5687-95. Chemical & Physical Properties Molecular Formula C46H77NO17 Exact Mass 915.519165 PSA 238.67000 Index of Refraction 1.549 InChIKey WBPYTXDJUQJLPQ-GSDFIKGFSA-N |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Danger Regulations: 3077 International Maritime Transport Danger Regulations: 3077 International Air Transport Danger Regulations: 3077 14.2 United Nations shipping name European land transport hazard regulations: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Tylosin) IMDG Code: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Tylosin) International air transport hazard regulations: Environmentally hazardous substance, solid, n.o.s. (Tylosin) 14.3 Transport hazard categories European land transport Dangerous Regulations: 9 International sea transport Dangerous Regulations: 9 International air transport Dangerous Regulations: 9 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: Yes International Maritime Transport Dangerous Regulations International Air Transport Dangerous Regulations: Yes Marine Pollutants (Yes/No): Yes 14.6 Special reminder to users further information Dangerous goods are individually packaged, with liquids exceeding 5 liters or solids exceeding 5 kilograms. The outer packaging of each independent package and the combined independent inner package must have EHS on it. Identification (according to European ADR Regulation 2.2.9.1.10, IMDG Regulation 2.10.3), |
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