
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 89785-84-2 |
| Catalog No. | 2A-9012593 |
| Chinese Name | 他唑巴坦钠 |
| Synonyms | Tazobactam Sodium; MFCD00917472; Tazobactam sodium salt; CL 307,579 |
| Molecular Formula | C10H11N4NaO5S |
| Molecular Weight | 322.27 |
| Purity | 90 |
| Density | 1.92 g/cm3 |
| Boiling Point | 707.1ºC at 760 mmHg |
| Melting Point | 140-147ºC |
| Appearance | powder or crystals |
| Water Solubility | H2O: 50 mg/mL, clear, colorless |
| Storage Condition | Store at 0-5°C |
| Application | Tazobactam sodium is a beta-lactamase inhibitor antibiotic. The combined use of Ceftolozane and Tazobactam can improve the antibacterial activity of Ceftolozane against a variety of ESBL-producing Ent |
| HTC | 2934999090 |
| PubChem ID | 329826726 |
| MDL Number | MFCD00917472 |
| SMILES | [Na+].C[C@]2(Cn1ccnn1)[C@@H](N3[C@@H](CC3=O)S2(=O)=O)C([O-])=O |
| InChI | 1S/C10H12N4O5S.Na/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19;/h2-3,7-8H,4-5H2,1H3,(H,16,17);/q;+1/p-1/t7-,8+,10+;/m1./s1 |
| InChI Key | RFMIKMMOLPNEDG-QVUDESDKSA-M |
| NACRES Code | NA.85 |
| UNSPSC | 51282127 |
| MSDS | msds/12593_1_89785_84_2.pdf |
| Use of | Tazobactam sodium is an antibiotic of the beta-lactamase inhibitor class. Ceftolozane combines with Tazobactam, extends the activity of ceftolozane against many ESBL-producing Enterobacteriaceae and some Bacteroides spp.. Properties Name tazobactam sodium Synonym More Synonyms Tazobactam Sodium Salt Biological Activity Description Tazobactam sodium is an antibiotic of the beta-lactamase inhibitor class. Ceftolozane combines with Tazobactam, extends the activity of ceftolozane against many ESBL-producing Enterobacteriaceae and some Bacteroides spp.. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial References [1]. Giacobbe DR, et al. Ceftolozane/tazobactam: place in therapy. Expert Rev Anti Infect Ther. 2018;16(4):307‐320. Chemical & Physical Properties Molecular Formula C10H11N4NaO5S Exact Mass 322.03500 PSA 133.67000 InChIKey ZUNWFYFXHGWFRA-QVUDESDKSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1- ylmethyl)-, 4,4-dioxide, sodium salt, (2S-(2-alpha,3-beta,5-alpha))- CAS REGISTRY NUMBER : 89785-84-2 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C10-H11-N4-O5-S.Na MOLECULAR WEIGHT : HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : Safety Information Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter Hazard Codes Xi RIDADR NONH for all modes of transport WGK Germany 3 RTECS XI0191500 HS Code 2934999090 Synthetic Route Total: 1 Page 2-METHANESULFON... CAS#:89789-07-1 Tazobactam Sodi... CAS#:89785-84-2 Literature: Journal of Medicinal Chemistry, , vol. 30, # 8 p. 1469 - 1474 Tazobactam CAS#:89786-04-9 Piperacillin CAS#:61477-96-1 Piperacillin Sodium CAS#:59703-84-3 Tazobactam Sodi... CAS#:89785-84-2 Literature: EP1759697 A1, ; Page/Page column 2-3 ; Precursor & DownStream Precursor 3 CAS#:89789-07-1 2-METHANESULFON... CAS#:89786-04-9 Tazobactam CAS#:61477-96-1 Piperacillin DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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