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T-2 toxin structure, CAS 21259-20-1

T-2 toxin

CAS Number21259-20-1

Synonyms4-β,15-Diacetoxy-8-α-(3-methylbutyryloxy)-3-α-hydroxy-12,13-epoxytrichothec-9-ene; (3a,4b,8a)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 4,15-diacetate 8-(3-methylbutanoate); Trichothec-9-ene-3-α,4-β,8-α,15-tetrol, 12,13-epoxy-, 4,15-diacetate 8-isovalerate; 3a-Hydroxy-4b,15-diacetoxy-8a-(3-methylbutyryloxy)-12,13-epoxy-D9-tricothecene; (3α,4β,8α)-4,15-bis(acetyloxy)-3-hydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate; 12,13-Epoxytrichothec-9-ene-3α,4β,8α,15-tetrol, 4,15-diacetate 8-isovalerate; 8a-(3-Methylbutyryloxy)-4b,15-diacetoxyscirp-9-en-3a-ol; Mycotoxin T-2; toxint2; alerate[qr]; 8α-(3-Methylbutyryloxy)-4β,15-diacetoxyscirp-9-en-3α-ol; othecene[qr]; Fusariotoxin T-2; Insariotoxin; FUSARITOXIN; MFCD00871255; Trichothec-9-ene-3α,4β,8α,15-tetrol, 12,13-epoxy-, 4,15-diacetate

Molecular FormulaC24H36O9

Molecular Weight466.52

Purity98%

Density1.3±0.1 g/cm3

Boiling Point544.9±50.0 °C at 760 mmHg

Melting Point151.5℃

Flash Point

Appearance

EINECS200-835-2

MSDSChineseEnglish

Symbol6.1(a)

Signal WordWarning

Cat. No.: 2A-9012559 Purity: 98%
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Quality Control of [ 21259-20-1 ] Purity: 98% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number21259-20-1
Catalog No.2A-9012559
Chinese NameT-2毒素
Synonyms4-β,15-Diacetoxy-8-α-(3-methylbutyryloxy)-3-α-hydroxy-12,13-epoxytrichothec-9-ene; (3a,4b,8a)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 4,15-diacetate 8-(3-methylbutanoate); Trichothec-9-ene-3-α,4-β,8-α,15-tetrol, 12,13-epoxy-, 4,15-diacetate 8-isovalerate; 3a-Hydroxy-4b,15-diacetoxy-8a-(3-methylbutyryloxy)-12,13-epoxy-D9-tricothecene; (3α,4β,8α)-4,15-bis(acetyloxy)-3-hydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate; 12,13-Epoxytrichothec-9-ene-3α,4β,8α,15-tetrol, 4,15-diacetate 8-isovalerate; 8a-(3-Methylbutyryloxy)-4b,15-diacetoxyscirp-9-en-3a-ol; Mycotoxin T-2; toxint2; alerate[qr]; 8α-(3-Methylbutyryloxy)-4β,15-diacetoxyscirp-9-en-3α-ol; othecene[qr]; Fusariotoxin T-2; Insariotoxin; FUSARITOXIN; MFCD00871255; Trichothec-9-ene-3α,4β,8α,15-tetrol, 12,13-epoxy-, 4,15-diacetate
Molecular FormulaC24H36O9
Molecular Weight466.52
Purity98
Density1.3±0.1 g/cm3
Boiling Point544.9±50.0 °C at 760 mmHg
Melting Point151.5℃
Storage Condition-20℃
PackagingI
ApplicationT-2 Toxin (T-2 Mycotoxin) is a mycotoxin produced by various Fusarium species in feed and grains. The LD50 values ​​of T-2 Toxin in small rats are 5.2 and 1.5 mg/kg BWa respectively. T-2 Toxin (T-2 My
EINECS200-835-2
PubChem ID329754792
MDL NumberMFCD00871255
SMILESCC1=C[C@]2([H])[C@]([C@]3(C)[C@@]4(OC4)[C@]([C@H](O)[C@H]3OC(C)=O)([H])O2)(COC(C)=O)C[C@@H]1OC(CC(C)C)=O
InChI1S/C24H34O9/c1-12(2)7-18(27)32-16-9-23(10-29-14(4)25)17(8-13(16)3)33-21-19(28)20(31-15(5)26)22(23,6)24(21)11-30-24/h8,12,16-17,19-21,28H,7,9-11H2,1-6H3/t16-,17+,19+,20+,21+,22+,23+,24-/m0/s1
InChI KeyBXFOFFBJRFZBQZ-QYWOHJEZSA-N
NACRES CodeNA.24
UNSPSC85151701
Hazard Symbols6.1(a)
MSDSmsds/12559_1_21259_20_1.pdf
BioactivityT-2 Toxin (T-2 Mycotoxin) is a toxic trichothecene mycotoxin produced by various Fusarium species in feedstuffs and cereal grains, LD50 values of T-2 Toxin in mice and rats are 5.2 and 1.5 mg/kg BWa,respectively [1]. T-2 Toxin (T-2 Mycotoxin) can be transformed into a variety of metabolite, the typical metabolites of T-2 toxin in animals are HT-2 toxin and T-2-triol, which are hydrolysates[1]. T-2 Toxin (T-2 Mycotoxin) is an inhibitor of protein synthesis resulting from binding peptidyltransferase, which is an integral part of the 60s ribosomal subunit. T-2 Toxin (T-2 Mycotoxin) inhibits the synthesis of DNA and RNA, interferes with the metabolism of membrane phospholipids, and increases the level of liver lipid peroxides[1]. T-2 Toxin (T-2 Mycotoxin) induces apoptosis in the immune system, gastrointestinal tissues, and fetal tissues[2]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Research Areas >> Metabolic Disease References [1]. Li Y, et al. T-2 toxin, a trichothecene mycotoxin: review of toxicity, metabolism, and analytical methods. J Agric Food Chem. 2011 Apr 27;59(8):3441-53. [2]. .Sun YX, et al. Toxicokinetics of T-2 toxin and its major metabolites in broiler chickens after intravenous and oral administration. J Vet Pharmacol Ther. 2015 Feb;38(1):80-5 Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 544.9±50.0 °C at 760 mmHg Melting Point 151.5℃ Molecular Formula C24H36O9 Molecular Weight 466.521 Flash Point 177.0±23.6 °C Exact Mass 466.220276 PSA 120.89000 LogP 2.25 Vapour Pressure 0.0±3.3 mmHg at 25°C Index of Refraction 1.547 InChIKey BXFOFFBJRFZBQZ-WTHKCUGASA-N SMILES CC(=O)OCC12CC(OC(=O)CC(C)C)C(C)=CC1OC1C(O)C(OC(C)=O)C2(C)C12CO2
Use ofProperties Name t-2 toxin Synonym More Synonyms T-2 TOXIN Biological Activity Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Research Areas >> Metabolic Disease References [1]. Li Y, et al. T-2 toxin, a trichothecene mycotoxin: review of toxicity, metabolism, and analytical methods. J Agric Food Chem. 2011 Apr 27;59(8):3441-53. [2]. .Sun YX, et al. Toxicokinetics of T-2 toxin and its major metabolites in broiler chickens after intravenous and oral administration. J Vet Pharmacol Ther. 2015 Feb;38(1):80-5 Chemical & Physical Properties Molecular Formula C24H36O9 Exact Mass 466.220276 PSA 120.89000 Index of Refraction 1.547 InChIKey BXFOFFBJRFZBQZ-WTHKCUGASA-N
Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Danger Regulations: 1648 International Maritime Transport Danger Regulations: 1648 International Air Transport Danger Regulations: 1648 14.2 United Nations shipping name European land transport hazard code: ACETONITRILE, solution IMDG Code: ACETONITRILE, solution IMDG: Acetonitrile, solution 14.3 Transport hazard categories European land transport Dangerous Regulations: 3 International sea transport Dangerous Regulations: 3 International air transport Dangerous Regulations: 3 14.4 Package group European Dangerous Regulations for land transport: II International Dangerous Regulations for sea transport: II International Dangerous Regulations for air transport: II 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available
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