CAS Number73384-60-8
Synonyms2-(2-methoxy-4-methylsulfinylphenyl)-1H-imidazo[4,5-b]pyridine; 2-(4-methanesulfinyl-2-methoxy-phenyl)-1(3)H-imidazo[4,5-b]pyridine; Sulmazol [INN-Spanish]; 2-(2-methoxy-4-methylsulfinyl-phenyl)-1H-imidazo [4,5-b]pyridine; sulmazol; Sulmazolum; Vardax; Sulmazolum [INN-Latin]; AR-L 115 BS
Molecular FormulaC14H13N3O2S
Molecular Weight287.34
Purity98.00%
Density1.45g/cm3
Boiling Point577.7ºC at 760 mmHg
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 73384-60-8 |
| Catalog No. | 2A-9012535 |
| Chinese Name | 苏马佐 |
| Synonyms | 2-(2-methoxy-4-methylsulfinylphenyl)-1H-imidazo[4,5-b]pyridine; 2-(4-methanesulfinyl-2-methoxy-phenyl)-1(3)H-imidazo[4,5-b]pyridine; Sulmazol [INN-Spanish]; 2-(2-methoxy-4-methylsulfinyl-phenyl)-1H-imidazo [4,5-b]pyridine; sulmazol; Sulmazolum; Vardax; Sulmazolum [INN-Latin]; AR-L 115 BS |
| Molecular Formula | C14H13N3O2S |
| Molecular Weight | 287.34 |
| Purity | 98.00 |
| Density | 1.45g/cm3 |
| Boiling Point | 577.7ºC at 760 mmHg |
| Application | Sumazole is a cardiotonic agent. Sulmazole is a competitive inhibitor of A1 adenosine receptors. Sumazole improves cardiac index and reduces pulmonary capillary wedge pressure [1]. |
| MDL Number | C14H13N3O2S |
| SMILES | COc1cc(S(C)=O)ccc1-c1nc2ncccc2[nH]1 |
| InChI | InChI=1S/C14H13N3O2S/c1-19-12-8-9(20(2)18)5-6-10(12)13-16-11-4-3-7-15-14(11)17-13/h3-8H,1-2H3,(H,15,16,17) |
| InChI Key | XMFCOYRWYYXZMY-UHFFFAOYSA-N |
| Hazard Symbols | Transport |
| MSDS | msds/12535_1_73384_60_8.pdf |
| Bioactivity | Sulmazole is a cardiotonic agent. Sulmazole has competitive inhibitory for A1 adenosine receptor. Sulmazole can improve cardiac index and reduce pulmonary capillary wedge pressure[1]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others In Vitro Sulmazole has competitive inhibitory for A1 adenosine receptors[1]. Sulmazole attenuates the capacity of GTP to inhibit adenylate cyclase activity and covalent modification of Gi by pertussis toxin treatment abolishes the capacity of sulmazole to mediate stimulation[1]. Sulmazole has stimulatory effect on adenylate cyclase activity in pertussis toxin-treated membranes[1]. Sulmazole mediates increases in cAMP accumulation by mechanisms other than phosphodiesterase inhibition, including A1 adenosine receptor antagonism and inhibition of Gi function[1]. Chemical & Physical Properties Density 1.45g/cm3 Boiling Point 577.7ºC at 760 mmHg Molecular Formula C14H13N3O2S Molecular Weight 287.33700 Flash Point 303.2ºC Exact Mass 287.07300 PSA 87.08000 LogP 3.23660 Index of Refraction 1.722 InChIKey XMFCOYRWYYXZMY-UHFFFAOYSA-N SMILES COc1cc(S(C)=O)ccc1-c1nc2ncccc2[nH]1 |
| Use of | Sulmazole is a cardiotonic agent. Sulmazole has competitive inhibitory for A1 adenosine receptor. Sulmazole can improve cardiac index and reduce pulmonary capillary wedge pressure[1]. Properties Name sulmazole Synonym More Synonyms Sulmazole Biological Activity Description Sulmazole is a cardiotonic agent. Sulmazole has competitive inhibitory for A1 adenosine receptor. Sulmazole can improve cardiac index and reduce pulmonary capillary wedge pressure[1]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others In Vitro Sulmazole has competitive inhibitory for A1 adenosine receptors[1]. Sulmazole attenuates the capacity of GTP to inhibit adenylate cyclase activity and covalent modification of Gi by pertussis toxin treatment abolishes the capacity of sulmazole to mediate stimulation[1]. Sulmazole has stimulatory effect on adenylate cyclase activity in pertussis toxin-treated membranes[1]. Sulmazole mediates increases in cAMP accumulation by mechanisms other than phosphodiesterase inhibition, including A1 adenosine receptor antagonism and inhibition of Gi function[1]. Chemical & Physical Properties Molecular Formula C14H13N3O2S Exact Mass 287.07300 PSA 87.08000 LogP 3.23660 Index of Refraction 1.722 InChIKey XMFCOYRWYYXZMY-UHFFFAOYSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available The company is not responsible for any damage caused by any operation or contact with the above products. For more terms of use, see invoice or package The reverse side of the mounting strip. |
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