
CAS Number201677-61-4
SynonymsSivelestat sodium hydrate; Sivelestat Sodium; Sivelestat sodium tetrahydrate; Elaspol; ONO-5046.Na; MFCD01937969; UNII-737RR8Y409; Sivelestat (sodium tetrahydrate)
Molecular FormulaC20H29N2NaO11S
Molecular Weight434.46 (anhydrous free acid basis)
Purity≥98 (HPLC)%
Appearancesolid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 201677-61-4 |
| Catalog No. | 2A-9012461 |
| Chinese Name | Sivelestat sodium tetrahydrate |
| Synonyms | Sivelestat sodium hydrate; Sivelestat Sodium; Sivelestat sodium tetrahydrate; Elaspol; ONO-5046.Na; MFCD01937969; UNII-737RR8Y409; Sivelestat (sodium tetrahydrate) |
| Molecular Formula | C20H29N2NaO11S |
| Molecular Weight | 434.46 (anhydrous free acid basis) |
| Purity | ≥98 (HPLC) |
| Appearance | solid |
| Storage Condition | -20℃ |
| Application | Sivelestat (ONO5046; LY544349; EI546) is a competitive inhibitor of human leukocyte elastase (neutrophil elastase) with an IC50 value of 44nM. It can also inhibit leukocyte elastase of mouse, rabbit a |
| SMILES | [S](=O)(=O)(Nc2c(cccc2)C(=O)NCC(=O)O)c1ccc(cc1)OC(=O)C(C)(C)C |
| InChI | 1S/C20H22N2O7S/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24/h4-11,22H,12H2,1-3H3,(H,21,25)(H,23,24) |
| InChI Key | BTGNGJJLZOIYID-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/12461_1_201677_61_4.pdf |
| Transport Info | Product name: Sivelast sodium tetrahydrate |
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