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Sesamin structure, CAS 607-80-7

Sesamin

CAS Number607-80-7

SynonymsSesamin; (7S,7'S,8R,8'R)-sesamin; 5,5'-(1S,3aR,4S,6aR)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diylbis(1,3-benzodioxole); (+)-Sesamin; Pseudocubebin; d-Sesamin; SesameP.E.; SezaMin; FAGAROL

Molecular FormulaC20H18O6

Molecular Weight354.35

Purity≥98 (HPLC)%

Density1.4±0.1 g/cm3

Boiling Point504.4±50.0 °C at 760 mmHg

Melting Point122-124ºC

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

SymbolTransport

Signal WordWarning

Cat. No.: 2A-9012428 Purity: ≥98 (HPLC)%
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Quality Control of [ 607-80-7 ] Purity: ≥98 (HPLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number607-80-7
Catalog No.2A-9012428
Chinese Name芝麻素
SynonymsSesamin; (7S,7'S,8R,8'R)-sesamin; 5,5'-(1S,3aR,4S,6aR)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diylbis(1,3-benzodioxole); (+)-Sesamin; Pseudocubebin; d-Sesamin; SesameP.E.; SezaMin; FAGAROL
Molecular FormulaC20H18O6
Molecular Weight354.35
Purity≥98 (HPLC)
Density1.4±0.1 g/cm3
Boiling Point504.4±50.0 °C at 760 mmHg
Melting Point122-124ºC
Appearancepowder
Water SolubilitySoluble in: chloroform
Storage Condition−20°C
ApplicationSesamin, a lignan abundant in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin has potent neuroprotective effects against cerebral
HTC2932999099
MDL NumberMFCD00216134
SMILESC1Oc2ccc(cc2O1)[C@H]3OC[C@H]4[C@@H]3CO[C@@H]4c5ccc6OCOc6c5
InChI1S/C20H18O6/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19+,20+/m0/s1
InChI KeyPEYUIKBAABKQKQ-AFHBHXEDSA-N
NACRES CodeNA.25
UNSPSC12352205
Hazard SymbolsTransport
MSDSmsds/12428_1_607_80_7.pdf
BioactivitySesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease Target delta 5 desaturase[1] In Vitro Pretreated with sesamin, Excess generation of nitric oxide in lipopolysaccharide-stimulated rat primary microglia cells was significantly attenuated[1]. In Vivo Sesamin (o.p.; 20 mg/kg/day) significantly reduces the infarct size by approximately 50% in male gerbils (60-85 g)[1]. References [1]. Cheng FC, et al. Neuroprotective effects of sesamin and sesamolin on gerbil brain in cerebral ischemia. Int J Biomed Sci. 2006 Sep;2(3):284-8. [2]. Shimizu S, et al. Sesamin is a potent and specific inhibitor of delta 5 desaturase in polyunsaturated fatty acidbiosynthesis. Lipids. 1991 Jul;26(7):512-6. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 504.4±50.0 °C at 760 mmHg Melting Point 122-124ºC Molecular Formula C20H18O6 Molecular Weight 354.353 Flash Point 212.3±30.0 °C Exact Mass 354.110352 PSA 55.38000 LogP 3.32 Vapour Pressure 0.0±1.2 mmHg at 25°C Index of Refraction 1.623 InChIKey PEYUIKBAABKQKQ-AFHBHXEDSA-N SMILES c1cc2c(cc1C1OCC3C(c4ccc5c(c4)OCO5)OCC13)OCO2 Storage condition −20°C
Use ofSesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2]. Properties Articles47 Name (+)-sesamin Synonym More Synonyms Sesamin Biological Activity Description Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease delta 5 desaturase[1] In Vitro Pretreated with sesamin, Excess generation of nitric oxide in lipopolysaccharide-stimulated rat primary microglia cells was significantly attenuated[1]. References [1]. Cheng FC, et al. Neuroprotective effects of sesamin and sesamolin on gerbil brain in cerebral ischemia. Int J Biomed Sci. 2006 Sep;2(3):284-8. [2]. Shimizu S, et al. Sesamin is a potent and specific inhibitor of delta 5 desaturase in polyunsaturated fatty acidbiosynthesis. Lipids. 1991 Jul;26(7):512-6. Chemical & Physical Properties Molecular Formula C20H18O6 Exact Mass 354.110352 PSA 55.38000 Index of Refraction 1.623 InChIKey PEYUIKBAABKQKQ-AFHBHXEDSA-N
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
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