| Chemical & Physical Properties | |
|---|---|
| CAS Number | 159912-53-5 |
| Catalog No. | 2A-9012365 |
| Chinese Name | 沙可美林 |
| Synonyms | Sabcomeline; Sabcomeline [INN:BAN] |
| Molecular Formula | C10H15N3O |
| Molecular Weight | 193.25 |
| Purity | 98 |
| Density | 1.25 |
| Boiling Point | 278ºC |
| Application | Sabcomeline (SB-202026) is a potent, functionally selective muscarinic M1 receptor partial agonist that improves cognition. Sabcomeline can be used in Alzheimer's disease research[1][2]. |
| HTC | 2933990090 |
| MDL Number | C10H15N3O |
| SMILES | CON=C(C#N)C1CN2CCC1CC2 |
| InChI Key | IQWCBYSUUOFOMF-VIFPVBQESA-N |
| MSDS | msds/12365_1_159912_53_5.pdf |
| Use of | Sabcomeline (SB-202026) is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline can be used for Alzheimer's disease research[1][2]. Properties Name (3Z,3R)-N-methoxy-1-azabicyclo[2.2.2]octane-3-carboximidoyl cyanide Synonym More Synonyms Sabcomeline Biological Activity Description Sabcomeline (SB-202026) is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline can be used for Alzheimer's disease research[1][2]. Related Catalog Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease Muscarinic M1 receptor[1][2] References [1]. Hosoi R, et al. Effect of sabcomeline on muscarinic and dopamine receptor binding in intact mouse brain. Ann Nucl Med. 2003;17(2):123-130. [2]. Hatcher JP, et al. Sabcomeline (SB-202026), a functionally selective M1 receptor partial agonist, reverses delay-induced deficits in the T-maze. Psychopharmacology (Berl). 1998;138(3-4):275-282. Chemical & Physical Properties Molecular Formula C10H15N3O Exact Mass 193.12200 PSA 48.62000 LogP 0.79208 InChIKey IQWCBYSUUOFOMF-VIFPVBQESA-N Safety Information HS Code 2933990090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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