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Ryanodine structure, CAS 15662-33-6

Ryanodine

CAS Number15662-33-6

SynonymsRyanodine; Ryanex; lot 704RWP-1; RYANODOL 3-(1H-PYRROLE-2-CARBOXYLATE); RYANADOL; [3H]-Ryanodine; EINECS 239-732-2; Ryanexcel; ryania; ryanexel; bonideryatox; Ryanicide; ryaniapowder

Molecular FormulaC25H35NO9

Molecular Weight493.55

Purity≥98 (HPLC)%

Density1.6±0.1 g/cm3

Boiling Point714.2±60.0 °C at 760 mmHg

Melting Point

Flash Point

Appearancesolid

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9012362 Purity: ≥98 (HPLC)%
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Quality Control of [ 15662-33-6 ] Purity: ≥98 (HPLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number15662-33-6
Catalog No.2A-9012362
Chinese Name鱼尼汀
SynonymsRyanodine; Ryanex; lot 704RWP-1; RYANODOL 3-(1H-PYRROLE-2-CARBOXYLATE); RYANADOL; [3H]-Ryanodine; EINECS 239-732-2; Ryanexcel; ryania; ryanexel; bonideryatox; Ryanicide; ryaniapowder
Molecular FormulaC25H35NO9
Molecular Weight493.55
Purity≥98 (HPLC)
Density1.6±0.1 g/cm3
Boiling Point714.2±60.0 °C at 760 mmHg
Appearancesolid
Storage ConditionThe warehouse is ventilated and dried at low tempe
ApplicationRyanodine is a cell-permeable ryanodine receptor modulator. Depending on its concentration, Ryanodine can stimulate or inhibit Ryanodine-mediated Ca2+ release. Toxic diterpenes found in Ryania specios
MDL NumberMFCD00151119
SMILES[nH]1c(ccc1)C(=O)O[C@H]2[C@@]3([C@]4([C@]65O[C@]([C@]4([C@@]2(O)C(C)C)C)(C[C@]3([C@]6(CC[C@@H]([C@H]5O)C)O)C)O)O)O
InChI1S/C25H35NO9/c1-12(2)22(31)17(34-16(28)14-7-6-10-26-14)23(32)18(4)11-21(30)19(22,5)25(23,33)24(35-21)15(27)13(3)8-9-20(18,24)29/h6-7,10,12-13,15,17,26-27,29-33H,8-9,11H2,1-5H3/t13-,15+,17+,18-,19-,20-,21-,22+,23+,24+,25+/m0/s1
InChI KeyJJSYXNQGLHBRRK-YSOSZROBSA-N
NACRES CodeNA.77
UNSPSC12352200
MSDSmsds/12362_1_15662_33_6.pdf
BioactivityRyanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease Target Ryanodine receptor[1] In Vivo Ryanodine (100-5000 nM, 30-120 mintutes) irreversibly depresses twitch and tetanic tension of both fast and slow muscle in a dose-related manner[1]. At concentrations above 250 nM, ryanodine induces a slowly developing, dose dependent contracture which could not be blocked by 5 mMCo2+[1]. References [1]. Meissner G, et al. Ryanodine activation and inhibition of the Ca2+ release channel of sarcoplasmic reticulum. J Biol Chem. 1986 May 15;261(14):6300-6. [2]. Fryer MW, et al. The action of ryanodine on rat fast and slow intact skeletal muscles. J Physiol. 1989 Jul;414:399-413. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Boiling Point 714.2±60.0 °C at 760 mmHg Molecular Formula C25H35NO9 Molecular Weight 493.547 Flash Point 385.7±32.9 °C Exact Mass 493.231171 PSA 172.70000 LogP 3.86 Vapour Pressure 0.0±2.4 mmHg at 25°C Index of Refraction 1.685 InChIKey JJSYXNQGLHBRRK-HAGUEVJCSA-N SMILES CC1CCC2(O)C3(C)CC4(O)OC2(C1O)C1(O)C3(O)C(OC(=O)c2ccc[nH]2)C(O)(C(C)C)C41C
Use ofRyanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa. Properties Articles63 Name ryanodine Synonym More Synonyms Ryanodine Biological Activity Description Ryanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease Ryanodine receptor[1] References [1]. Meissner G, et al. Ryanodine activation and inhibition of the Ca2+ release channel of sarcoplasmic reticulum. J Biol Chem. 1986 May 15;261(14):6300-6. [2]. Fryer MW, et al. The action of ryanodine on rat fast and slow intact skeletal muscles. J Physiol. 1989 Jul;414:399-413. Chemical & Physical Properties Molecular Formula C25H35NO9 Exact Mass 493.231171 PSA 172.70000 Index of Refraction 1.685 InChIKey JJSYXNQGLHBRRK-HAGUEVJCSA-N
Transport InfoProduct name: Ryanodine
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