| Chemical & Physical Properties | |
|---|---|
| CAS Number | 5142-22-3 |
| Catalog No. | 2A-9001228 |
| Chinese Name | 1-甲基腺嘌呤 |
| Synonyms | 1-METHYLADENINE; 1-Methyladenine |
| Molecular Formula | C6H7N5 |
| Molecular Weight | 149.15300 |
| Purity | 98 |
| Density | 1.6 g/cm3 |
| Boiling Point | 240.1ºC at 760 mmHg |
| Melting Point | > 300ºC |
| Appearance | Light yellow fine crystalline powder |
| Storage Condition | ?20°C |
| Application | 1-Methyladenine is a product of alkylation damage in DNA and can be repaired through damage reversal by oxidative demethylation. |
| EINECS | 225-907-0 |
| HTC | 2933990090 |
| SMILES | Cn1cnc2ncnc2c1N |
| InChI | InChI=1S/C6H7N5/c1-11-3-10-6-4(5(11)7)8-2-9-6/h2-3H,7H2,1H3 |
| InChI Key | InChIKey=HPZMWTNATZPBIH-UHFFFAOYSA-N |
| Bioactivity | 1-Methyladenine is a product of alkylation damage in DNA which can be repaired by damage reversal by oxidative demethylation. Related Catalog Natural Products >> Others Research Areas >> Others Target Human Endogenous Metabolite References [1]. Falnes PØ, et al. Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins. Nucleic Acids Res. 2004 Dec 1;32(21):6260-7. Print 2004. [2]. Yang H, et al. Effect of 1-methyladenine on double-helical DNA structures. FEBS Lett. 2008 May 14;582(11):1629-33. Chemical & Physical Properties Density 1.6 g/cm3 Boiling Point 240.1ºC at 760 mmHg Melting Point > 300ºC Molecular Formula C6H7N5 Molecular Weight 149.15300 Flash Point 99ºC Exact Mass 149.07000 PSA 69.62000 LogP 0.52670 Index of Refraction 1.807 Storage condition ?20°C |
| Use of | 1-Methyladenine is a product of alkylation damage in DNA which can be repaired by damage reversal by oxidative demethylation. Properties Name 1-methyladenine Synonym More Synonyms 1-Methyladenine Biological Activity Description 1-Methyladenine is a product of alkylation damage in DNA which can be repaired by damage reversal by oxidative demethylation. Related Catalog Natural Products >> Others Research Areas >> Others Human Endogenous Metabolite References [1]. Falnes PØ, et al. Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins. Nucleic Acids Res. 2004 Dec 1;32(21):6260-7. Print 2004. Chemical & Physical Properties Molecular Formula C6H7N5 Exact Mass 149.07000 PSA 69.62000 LogP 0.52670 Index of Refraction 1.807 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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