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2-AMINO-8-HYDROXY-1H-PURIN-6(7H)-ONE

Name: 2-AMINO-8-HYDROXY-1H-PURIN-6(7H)-ONE
Brand: 2A Biotech
SKU: 2A-0118892

CAS Number5614-64-2

Synonyms8-OH-GUA; 7,8-DIHYDRO-8-OXOGUANINE; 2-AMINO-6,8-DIHYDROXYPURINE; 8-Hydroxy-guanin; 8-Oxo-7,8-dihydroguanine; 8-OXOGUANINE; 2-amino-7,9-dihydro-1H-purine-6,8-dione; 2-AMINO-6,8-PURINEDIOL; 8-Oxodihydroguanine; 2-aminopurine-6,8-diol; 8-OXOG; 8-HYDROXYGUANINE; EINECS 227-035-6

Molecular FormulaC5H5N5O2

Molecular Weight167.13

Purity96+%

Density2.49g/cm3

Boiling Point327.7ºC at 760 mmHg

Melting Point>400ºC dec.

EINECS0

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Cat. No.: 2A-0118892 Purity: 96+%

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Quality Control of [ 5614-64-2 ] Purity: 96+% SDS Specification MoL

Chemical & Physical Properties
CAS Number	5614-64-2
Catalog No.	2A-0118892
Chinese Name	2-氨基-6,8-二羟基嘌呤
Synonyms	8-OH-GUA; 7,8-DIHYDRO-8-OXOGUANINE; 2-AMINO-6,8-DIHYDROXYPURINE; 8-Hydroxy-guanin; 8-Oxo-7,8-dihydroguanine; 8-OXOGUANINE; 2-amino-7,9-dihydro-1H-purine-6,8-dione; 2-AMINO-6,8-PURINEDIOL; 8-Oxodihydroguanine; 2-aminopurine-6,8-diol; 8-OXOG; 8-HYDROXYGUANINE; EINECS 227-035-6
Molecular Formula	C5H5N5O2
Molecular Weight	167.13
Purity	96+
Density	2.49g/cm3
Boiling Point	327.7ºC at 760 mmHg
Melting Point	>400ºC dec.
Storage Condition	Avoid light, keep in a cool and dry place, sealed
Application	8-Hydroxyguanine is the primary premutagenic damage produced by reactive oxygen species. It results in G-T and A-C substitutions.
EINECS	0
HTC	2933990090
UN(IATA)	0
MDL Number	C5H5N5O2
SMILES	NC1=NC(=O)C2=C(N1)NC(=O)N2
InChI	InChI=1S/C5H5N5O2/c6-4-8-2-1(3(11)10-4)7-5(12)9-2/h(H5,6,7,8,9,10,11,12)
InChI Key	InChIKey=CLGFIVUFZRGQRP-UHFFFAOYSA-N
Hazard Symbols	transportation
Bioactivity	8-Hydroxyguanine is a major pre-mutagenic lesion generated from reactive oxygen species. It causes G-T and A-C substitutions. Related Catalog Natural Products >> Others Research Areas >> Others Target Human Endogenous Metabolite References [1]. Arai T, et al. High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress. Carcinogenesis. 2002 Dec;23(12):2005-10. [2]. Floyd RA, et al. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis. 1990 Sep;11(9):1447-50. [3]. Cheng KC, et al. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions. J Biol Chem. 1992 Jan 5;267(1):166-72. Chemical & Physical Properties Density 2.49g/cm3 Boiling Point 327.7ºC at 760 mmHg Melting Point >400ºC dec. Molecular Formula C5H5N5O2 Molecular Weight 167.12500 Flash Point 152ºC Exact Mass 167.04400 PSA 120.94000 Index of Refraction 2.156
Use of	8-Hydroxyguanine is a major pre-mutagenic lesion generated from reactive oxygen species. It causes G-T and A-C substitutions. Properties Name 7,8-dihydro-8-oxoguanine Synonym More Synonyms 8-Hydroxyguanine Biological Activity Description 8-Hydroxyguanine is a major pre-mutagenic lesion generated from reactive oxygen species. It causes G-T and A-C substitutions. Related Catalog Natural Products >> Others Research Areas >> Others Human Endogenous Metabolite References [1]. Arai T, et al. High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress. Carcinogenesis. 2002 Dec;23(12):2005-10. [2]. Floyd RA, et al. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis. 1990 Sep;11(9):1447-50. [3]. Cheng KC, et al. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions. J Biol Chem. 1992 Jan 5;267(1):166-72. Chemical & Physical Properties Molecular Formula C5H5N5O2 Exact Mass 167.04400 PSA 120.94000 Index of Refraction 2.156
Tax Rebate	13.0%
Supervision	None. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport Info	Product name: Purity: 98.0%
MSDS Transport Info	Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available

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2-AMINO-8-HYDROXY-1H-PURIN-6(7H)-ONE

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