CAS Number53716-50-0
Synonymssystamex; Methyl [5-(Phenylsulfinyl)benzimidazol-2-yl]carbamate; MFCD00133728; UNII:OMP2H17F9E; CFDZ; LODITAC; synanthic; hoe8105; Carbamic acid, N-[5-(phenylsulfinyl)-1H-benzimidazol-2-yl]-, methyl ester; Oxfendazole; EINECS 258-714-5; Methyl 5-(phenylsulfinyl)-benzimidazol-2-carbamate; rs-8858; Methyl [5-(phenylsulfinyl)-1H-benzimidazol-2-yl]carbamate; repidose; ofdz; [5-(Phenylsulfinyl)benzimidazol-2-yl]carbamic Acid Methyl Ester; Fenbendazole Sulfoxide
Molecular FormulaC15H13N3O3S
Molecular Weight315.35
Purity98%
Density1.5±0.1 g/cm3
Melting Point253ºC
AppearanceWhite to light yellow powder
EINECS258-714-5
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 53716-50-0 |
| Catalog No. | 2A-9011819 |
| Chinese Name | 奥芬达唑 |
| Synonyms | systamex; Methyl [5-(Phenylsulfinyl)benzimidazol-2-yl]carbamate; MFCD00133728; UNII:OMP2H17F9E; CFDZ; LODITAC; synanthic; hoe8105; Carbamic acid, N-[5-(phenylsulfinyl)-1H-benzimidazol-2-yl]-, methyl ester; Oxfendazole; EINECS 258-714-5; Methyl 5-(phenylsulfinyl)-benzimidazol-2-carbamate; rs-8858; Methyl [5-(phenylsulfinyl)-1H-benzimidazol-2-yl]carbamate; repidose; ofdz; [5-(Phenylsulfinyl)benzimidazol-2-yl]carbamic Acid Methyl Ester; Fenbendazole Sulfoxide |
| Molecular Formula | C15H13N3O3S |
| Molecular Weight | 315.35 |
| Purity | 98 |
| Density | 1.5±0.1 g/cm3 |
| Melting Point | 253ºC |
| Appearance | White to light yellow powder |
| Storage Condition | Sealed, stored at 2ºC -8ºC |
| Application | Oxfendazole is the sulfoxide form of fenbendazole, which fights parasites. |
| EINECS | 258-714-5 |
| PubChem ID | 329754866 |
| MDL Number | MFCD00801063 |
| SMILES | COC(=O)Nc1nc2cc(ccc2[nH]1)S(=O)c3ccccc3 |
| InChI | 1S/C15H13N3O3S/c1-21-15(19)18-14-16-12-8-7-11(9-13(12)17-14)22(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19) |
| InChI Key | BEZZFPOZAYTVHN-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/11819_1_53716_50_0.pdf |
| Bioactivity | Oxfendazole is the sulfoxide form of fenbendazole which is a broad spectrum benzimidazole anthelmintic. Target: AntiparasiticOxfendazole is the sulfoxide form of fenbendazole, a broad spectrum benzimidazole anthelmintic. Its main use is for protecting livestock against roundworm, strongyles and pinworms.[1]. Pigs in the treated group received Oxfendazole orally at 30 mg/kg dose. At five days post-treatment, animals were sacrificed and the clinical efficacy of the Oxfendazole treatment was established following the currently available WAAVP guidelines for a controlled efficacy test. None of the animals involved in this experiment showed any adverse events during the study. Oxfendazole treatment given as a single 30 mg/kg oral dose showed a 100% efficacy against all the nematode parasites present in the three experiments. In conclusion, under the current experimental conditions, Oxfendazole orally administered to naturally parasitized piglets at a single dose of 30 mg/kg was safe and highly efficacious (100%) against adult stages of A. suum, Oesophagostomum spp., T. suis and Metastrongylus spp [1]. Related Catalog Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection References [1]. http://www.chemicalland21.com/lifescience/phar/OXFENDAZOLE.htm [2]. Alvarez, L., et al., Efficacy of a single high oxfendazole dose against gastrointestinal nematodes in naturally infected pigs. Veterinary parasitology, 2013. 194(1): p. 70-74. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Melting Point 253ºC Molecular Formula C15H13N3O3S Molecular Weight 315.347 Exact Mass 315.067749 PSA 103.29000 LogP 1.36 Index of Refraction 1.736 InChIKey BEZZFPOZAYTVHN-UHFFFAOYSA-N SMILES COC(=O)Nc1nc2ccc(S(=O)c3ccccc3)cc2[nH]1 Storage condition 2-8°C |
| Use of | Properties Articles27 Name oxfendazole Synonym More Synonyms Oxfendazole Biological Activity Related Catalog Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection References [2]. Alvarez, L., et al., Efficacy of a single high oxfendazole dose against gastrointestinal nematodes in naturally infected pigs. Veterinary parasitology, 2013. 194(1): p. 70-74. Chemical & Physical Properties Molecular Formula C15H13N3O3S Exact Mass 315.067749 PSA 103.29000 Index of Refraction 1.736 InChIKey BEZZFPOZAYTVHN-UHFFFAOYSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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