CAS Number128794-94-5
SynonymsCellcept; Mycophenolate mofetil (CellCept); Mycophenolatemofetil; MYCOPHENOLATE MOFITILE; MYCOPHENOLATE; RS 61443-190; MYCOPHENALATE MOFETIL; MYCOPHENOLATE MOFETIL(CELLCEPT); Mycophenolate mofetil; MFCD00867568; Mycophenolic acid morpholinoethyl ester
Molecular FormulaC23H31NO7
Molecular Weight433.49
Purity98%
Density1.2±0.1 g/cm3
Boiling Point637.6±55.0 °C at 760 mmHg
Melting Point95-96ºC
AppearanceWhite to off-white crystalline powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 128794-94-5 |
| Catalog No. | 2A-9011531 |
| Chinese Name | 吗替麦考酚酯 |
| Synonyms | Cellcept; Mycophenolate mofetil (CellCept); Mycophenolatemofetil; MYCOPHENOLATE MOFITILE; MYCOPHENOLATE; RS 61443-190; MYCOPHENALATE MOFETIL; MYCOPHENOLATE MOFETIL(CELLCEPT); Mycophenolate mofetil; MFCD00867568; Mycophenolic acid morpholinoethyl ester |
| Molecular Formula | C23H31NO7 |
| Molecular Weight | 433.49 |
| Purity | 98 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 637.6±55.0 °C at 760 mmHg |
| Melting Point | 95-96ºC |
| Appearance | White to off-white crystalline powder |
| Water Solubility | Water solubility: insoluble; water solubility: 43 |
| Storage Condition | Store at RT |
| Application | Mycophenolate Mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH) with IC50 of 39 nM and 27 nM respectively. |
| PubChem ID | 329750505 |
| MDL Number | MFCD00867568 |
| SMILES | COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CCC(=O)OCCN3CCOCC3 |
| InChI | 1S/C23H31NO7/c1-15(5-7-19(25)30-13-10-24-8-11-29-12-9-24)4-6-17-21(26)20-18(14-31-23(20)27)16(2)22(17)28-3/h4,26H,5-14H2,1-3H3/b15-4+ |
| InChI Key | RTGDFNSFWBGLEC-SYZQJQIISA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/11531_1_128794_94_5.pdf |
| Bioactivity | Mycophenolate Mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH) with IC50s of 39 nM and 27 nM, respectively. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Cancer References [1]. Nakanishi, T., et al., Effect of the inosine 5'-monophosphate dehydrogenase inhibitor BMS-566419 on rat cardiac allograft rejection. Int Immunopharmacol, 2010. 10(1): p. 91-7. [2]. Dehghani, F., et al., Inhibition of microglial and astrocytic inflammatory responses by the immunosuppressant mycophenolate mofetil. Neuropathol Appl Neurobiol, 2010. 36(7): p. 598-611. [3]. Ozgen, M., et al., Mycophenolate mofetil and daclizumab targeting T lymphocytes in bleomycin-induced experimental scleroderma. Clin Exp Dermatol, 2012. 37(1): p. 48-54. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 637.6±55.0 °C at 760 mmHg Melting Point 95-96ºC Molecular Formula C23H31NO7 Molecular Weight 433.495 Flash Point 339.4±31.5 °C Exact Mass 433.210052 PSA 94.53000 LogP 3.15 Vapour Pressure 0.0±2.0 mmHg at 25°C Index of Refraction 1.557 InChIKey RTGDFNSFWBGLEC-SYZQJQIISA-N SMILES COc1c(C)c2c(c(O)c1CC=C(C)CCC(=O)OCCN1CCOCC1)C(=O)OC2 Storage condition Store at RT |
| Use of | Mycophenolate Mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH) with IC50s of 39 nM and 27 nM, respectively. Properties Articles130 Name mycophenolate mofetil Synonym More Synonyms Mycophenolate mofetil Biological Activity Description Mycophenolate Mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH) with IC50s of 39 nM and 27 nM, respectively. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Cancer References [1]. Nakanishi, T., et al., Effect of the inosine 5'-monophosphate dehydrogenase inhibitor BMS-566419 on rat cardiac allograft rejection. Int Immunopharmacol, 2010. 10(1): p. 91-7. [2]. Dehghani, F., et al., Inhibition of microglial and astrocytic inflammatory responses by the immunosuppressant mycophenolate mofetil. Neuropathol Appl Neurobiol, 2010. 36(7): p. 598-611. [3]. Ozgen, M., et al., Mycophenolate mofetil and daclizumab targeting T lymphocytes in bleomycin-induced experimental scleroderma. Clin Exp Dermatol, 2012. 37(1): p. 48-54. Chemical & Physical Properties Molecular Formula C23H31NO7 Exact Mass 433.210052 PSA 94.53000 Index of Refraction 1.557 InChIKey RTGDFNSFWBGLEC-SYZQJQIISA-N Storage condition Store at RT |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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