
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 169209-66-9 |
| Catalog No. | 2A-0114923 |
| Chinese Name | (±)-Alpha-甲基-(4-四氮唑苯)日氨酸 |
| Synonyms | MFCD00672653; 2-amino-2-[4-(tetrazol-1-yl)phenyl]propanoic acid |
| Molecular Formula | C10H11N5O2 |
| Molecular Weight | 272.11 |
| Purity | 96+ |
| Storage Condition | Storage method: 2 -8 °C |
| Application | MTPG is a potent mGluR2 and mGluR3 antagonist. MTPG can block cerebral ischemic tolerance induced by cerebral ischemic preconditioning. MTPG also significantly weakens the inhibitory effect of L-CCG-1 |
| EINECS | 0 |
| HTC | 2933990090 |
| UN(IATA) | 0 |
| PubChem ID | 329830302 |
| MDL Number | MFCD17214381 |
| NACRES Code | NA.21 |
| UNSPSC | 12352200 |
| Hazard Symbols | transportation |
| Bioactivity | MTPG is a potent mGluR2 and mGluR3 antagonist. MTPG can block the induction of brain ischemic tolerance induced by cerebral ischemic preconditioning. MTPG also significantly attenuates the inhibitory effect of L-CCG-1 on the KCl-evoked dopamine release[1]. Related Catalog Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease Target mGluR2, mGluR 3[1] References [1]. Chaki S, et al. Group II metabotropic glutamate receptor-mediated regulation of dopamine release from slices of rat nucleus accumbens. Neurosci Lett. 2006;404(1-2):182-186. [2]. Feng RF, Li WB, Liu HQ, et al. Sheng Li Xue Bao. 2003;55(3):303-310. Chemical & Physical Properties Molecular Formula C10H11N5O2 Molecular Weight 233.23 Exact Mass 233.09100 PSA 106.92000 LogP 0.62110 |
| Use of | MTPG is a potent mGluR2 and mGluR3 antagonist. MTPG can block the induction of brain ischemic tolerance induced by cerebral ischemic preconditioning. MTPG also significantly attenuates the inhibitory effect of L-CCG-1 on the KCl-evoked dopamine release[1]. Properties Name (±)-α-Methyl-(4-tetrazolylphenyl)glycine Synonym More Synonyms MTPG Biological Activity Description MTPG is a potent mGluR2 and mGluR3 antagonist. MTPG can block the induction of brain ischemic tolerance induced by cerebral ischemic preconditioning. MTPG also significantly attenuates the inhibitory effect of L-CCG-1 on the KCl-evoked dopamine release[1]. Related Catalog Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease mGluR2, mGluR 3[1] References [1]. Chaki S, et al. Group II metabotropic glutamate receptor-mediated regulation of dopamine release from slices of rat nucleus accumbens. Neurosci Lett. 2006;404(1-2):182-186. [2]. Feng RF, Li WB, Liu HQ, et al. Sheng Li Xue Bao. 2003;55(3):303-310. Chemical & Physical Properties Molecular Formula C10H11N5O2 Exact Mass 233.09100 PSA 106.92000 LogP 0.62110 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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