CAS Number130727-41-2
SynonymsTriethylene glycol mono-11-mercaptoundecyl ether; 20-sulfanyl-3,6,9-trioxa-1-icosanol
Molecular FormulaHS(CH2)11(OCH2CH2)3OH
Molecular Weight336.53
Purity96+%
Density0.995 g/mL at 25ºC
Boiling Point446.5ºC at 760 mmHg
EINECS0
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 130727-41-2 |
| Catalog No. | 2A-0113667 |
| Chinese Name | 三(乙烯醇) 单-11-十一烷基硫醇 |
| Synonyms | Triethylene glycol mono-11-mercaptoundecyl ether; 20-sulfanyl-3,6,9-trioxa-1-icosanol |
| Molecular Formula | HS(CH2)11(OCH2CH2)3OH |
| Molecular Weight | 336.53 |
| Purity | 96+ |
| Density | 0.995 g/mL at 25ºC |
| Boiling Point | 446.5ºC at 760 mmHg |
| Storage Condition | Refrigerator, Under Inert Atmosphere |
| Application | Thiol-C9-PEG4 is a PROTAC linker, belonging to the PEG class. Can be used to synthesize PROTAC molecules. |
| EINECS | 0 |
| HTC | 2930909090 |
| UN(IATA) | 0 |
| PubChem ID | 24885143 |
| MDL Number | MFCD08457662 |
| SMILES | OCCOCCOCCOCCCCCCCCCCCS |
| InChI Key | FASSFROSROBIBE-UHFFFAOYSA-N |
| NACRES Code | NA.23 |
| UNSPSC | 12352103 |
| Hazard Symbols | transportation |
| Bioactivity | Thiol-C9-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target PEGs In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Density 0.995 g/mL at 25ºC Boiling Point 446.5ºC at 760 mmHg Molecular Formula C17H36O4S Molecular Weight 336.53000 Flash Point >110ºC Exact Mass 336.23300 PSA 86.72000 LogP 3.46920 Vapour Pressure 7.55E-10mmHg at 25°C Index of Refraction n 20/D 1.476 InChIKey FASSFROSROBIBE-UHFFFAOYSA-N SMILES OCCOCCOCCOCCCCCCCCCCCS Storage condition Refrigerator, Under Inert Atmosphere |
| Use of | Thiol-C9-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Name 2-[2-[2-(11-sulfanylundecoxy)ethoxy]ethoxy]ethanol Synonym More Synonyms Thiol-C9-PEG4 Biological Activity Description Thiol-C9-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Molecular Formula C17H36O4S Exact Mass 336.23300 PSA 86.72000 LogP 3.46920 InChIKey FASSFROSROBIBE-UHFFFAOYSA-N SMILES OCCOCCOCCOCCCCCCCCCCCS Storage condition Refrigerator, Under Inert Atmosphere |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information European Land Transport Dangerous Regulations: -International Maritime Transport Dangerous Regulations: -International Air Transport Dangerous Regulations: 3334 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods Aviation regulated liquid, n.o.s. (Triethylene glycol mono-11-mercaptoundecyl ether) 14.3 Transport hazard categories European land transport danger code: -International sea transport danger code: -International air transport danger code: 9 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Transport Dangerous Regulations: -International Air Transport Dangerous Regulations: III 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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