CAS Number5118-29-6
SynonymsMelitracen; Melitracene; Adaptol; Thymeol; Trausabun; Meltiracene; 9.9-Dimethyl-10-<3-dimethylamino-propyliden>-9.10-dihydro-anthracen; Dixeran
Molecular FormulaC21H25N
Molecular Weight327.89
Purity98.00%
Density1.046g/cm3
Boiling Point399.1ºC at 760mmHg
Appearancesolid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 5118-29-6 |
| Catalog No. | 2A-9011327 |
| Chinese Name | 美利蒽 |
| Synonyms | Melitracen; Melitracene; Adaptol; Thymeol; Trausabun; Meltiracene; 9.9-Dimethyl-10-<3-dimethylamino-propyliden>-9.10-dihydro-anthracen; Dixeran |
| Molecular Formula | C21H25N |
| Molecular Weight | 327.89 |
| Purity | 98.00 |
| Density | 1.046g/cm3 |
| Boiling Point | 399.1ºC at 760mmHg |
| Appearance | solid |
| Storage Condition | The warehouse is ventilated and dried at low tempe |
| Application | Melitracene is an orally active tricyclic antidepressant and a bipolar thymosin with activating properties. Melitracen inhibits 3H-5-HT and 14H-5-HT, with IC50 of 670nm and 5500nm respectively. Melitr |
| HTC | 2921499090 |
| MDL Number | MFCD00242905 |
| SMILES | [Cl-].[N+H](CCC=C1c2c(cccc2)C(c3c1cccc3)(C)C)(C)C |
| InChI | 1S/C21H25N.ClH/c1-21(2)19-13-7-5-10-17(19)16(12-9-15-22(3)4)18-11-6-8-14-20(18)21;/h5-8,10-14H,9,15H2,1-4H3;1H |
| InChI Key | RADLXCPDUXFGFF-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/11327_1_5118_29_6.pdf |
| Use of | Melitracen (Melitracene) is an orally active tricyclic antidepressant and it is also a bipolar thymoleptic with activating properties. Melitracen inhibits 3H-5-HT and 14H-5-HT with IC50s of 670 nM and 5500 nM, respectively. Melitracen can be used for the research of depression and anxiety[1][2]. Properties Name 3-(10,10-dimethylanthracen-9-ylidene)-N,N-dimethylpropan-1-amine Synonym More Synonyms Melitracen Biological Activity Description Melitracen (Melitracene) is an orally active tricyclic antidepressant and it is also a bipolar thymoleptic with activating properties. Melitracen inhibits 3H-5-HT and 14H-5-HT with IC50s of 670 nM and 5500 nM, respectively. Melitracen can be used for the research of depression and anxiety[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease IC50: 670 nM (3H-5-HT), 5500 nM (14H-5-HT)[2] References [1]. Shimamoto K, et al. Relationship between the restriction of food intake and Melitracen, an antidepressant, in the rat. Acta Sch Med Univ Kioto. 1967 Jul;40(1):25-37. Chemical & Physical Properties Molecular Formula C21H25N Exact Mass 291.19900 PSA 3.24000 LogP 4.70930 Index of Refraction 1.4900 (estimate) InChIKey GWWLWDURRGNSRS-UHFFFAOYSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : delta-(sup 9(10),gamma)-Anthracenepropylamine, N,N,10,10-tetramethyl- CAS REGISTRY NUMBER : LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : MOLECULAR WEIGHT : HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 25,519,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 25,519,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 25,519,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 25,519,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 25,519,1970 Safety Information HS Code 2921499090 Synthetic Route Total: 1 Page Melitracen hydr... CAS#:5447-86-9 3-Chloro-N,N-di... CAS#:109-54-6 Melitracen CAS#:5118-29-6 Literature: Holm,T. Acta Chemica Scandinavica (1947-1973), 1963 , vol. 17, p. 2437 - 2443 Precursor & DownStream Precursor 2 CAS#:5447-86-9 Melitracen hydr... CAS#:109-54-6 3-Chloro-N,N-di... DownStream 0 |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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