Home > Products > Pharmaceutical R&D Materials > Heterocyclic Building Blocks > 2,8-DIMETHYL-2,3,4,4A,5,9B-HEXAHYDRO-1H-PYRIDO[4,3-B]INDOLE

2,8-DIMETHYL-2,3,4,4A,5,9B-HEXAHYDRO-1H-PYRIDO[4,3-B]INDOLE

Name: 2,8-DIMETHYL-2,3,4,4A,5,9B-HEXAHYDRO-1H-PYRIDO[4,3-B]INDOLE
Brand: 2A Biotech
SKU: 2A-0112669

CAS Number17411-19-7

SynonymsCarbidine; Dicarbine

Molecular FormulaC13H18N2

Molecular Weight202.3

Purity96+%

Density1.043g/cm3

Boiling Point305.7ºC at 760mmHg

EINECS0

MSDSChinese English

Cat. No.: 2A-0112669 Purity: 96+%

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Quality Control of [ 17411-19-7 ] Purity: 96+% SDS Specification MoL

Chemical & Physical Properties
CAS Number	17411-19-7
Catalog No.	2A-0112669
Chinese Name	Dicarbine
Synonyms	Carbidine; Dicarbine
Molecular Formula	C13H18N2
Molecular Weight	202.3
Purity	96+
Density	1.043g/cm3
Boiling Point	305.7ºC at 760mmHg
Application	Dicarbine can block the distribution of dopamine receptors in different parts of the brain, inhibiting conditioned reflexes caused by stimulating the midbrain part of the reticular formation. Dicarbin
EINECS	0
HTC	2933990090
UN(IATA)	0
SMILES	Cc1ccc2c(c1)C1CN(C)CCC1N2
InChI	InChI=1S/C13H18N2.2ClH/c1-9-3-4-12-10(7-9)11-8-15(2)6-5-13(11)14-12;;/h3-4,7,11,13-14H,5-6,8H2,1-2H3;2*1H
InChI Key	CYJQCYXRNNCURD-UHFFFAOYSA-N
Use of	Dicarbine blocks dopamine receptors in various brain parts and prevents the depression of the conditioned defence reflexes caused by stimulation of the mesencephalic portion of the reticular formation. Dicarbine could be used to treat patients with schizophrenia and alcoholic psychosis in clinical[1][2]. Properties Name 2,8-dimethyl-1,3,4,4a,5,9b-hexahydropyrido[4,3-b]indole Synonym More Synonyms Dicarbine Biological Activity Description Dicarbine blocks dopamine receptors in various brain parts and prevents the depression of the conditioned defence reflexes caused by stimulation of the mesencephalic portion of the reticular formation. Dicarbine could be used to treat patients with schizophrenia and alcoholic psychosis in clinical[1][2]. Related Catalog Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease Dopamine receptor[1][2]. References [1]. Barkov NK, et al. [Effect of carbidine on conditioned defense reflexes]. Biull Eksp Biol Med. 1975 Apr;79(4):61-4. [2]. DICARBINE Chemical & Physical Properties Molecular Formula C13H18N2 Exact Mass 202.14700 PSA 15.27000 LogP 2.28410 Index of Refraction 1.554 InChIKey CYJQCYXRNNCURD-UHFFFAOYSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : 1H-Pyrido(4,3-b)indole, 2,3,4,4a,5,9b-hexahydro-2,8-dimethyl- CAS REGISTRY NUMBER : 17411-19-7 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C13-H18-N2 MOLECULAR WEIGHT : HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3983239 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3983239 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3983239 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3983239 Safety Information HS Code 2933990090 Synthetic Route Total: 1 Page 2,8-Dimethyl-2,... CAS#:19686-05-6 CAS#:17411-19-7 Literature: Kucherova, N. F.; Sipilina, N. M.; Novikova, N. N.; Silenko, I. D.; Rozenberg, S. G.; Zagorevskii, V. A. Chemistry of Heterocyclic Compounds (New York, NY, United States), 1980 , p. 1051 - 1053 Khimiya Geterotsiklicheskikh Soedinenii, 1980 , vol. 16, # 10 p. 1383 - 1386 Precursor & DownStream Precursor 1 CAS#:19686-05-6 2,8-Dimethyl-2,... DownStream 0
Tax Rebate	13.0%
Supervision	None. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport Info	Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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2,8-DIMETHYL-2,3,4,4A,5,9B-HEXAHYDRO-1H-PYRIDO[4,3-B]INDOLE

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