CAS Number57381-26-7
Synonyms2',5'-Dichlorobenzoguanamine; MFCD00866871; Irsogladin; 6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diamine; gaslon; Irsogladine; Dicloguamine
Molecular FormulaC9H7N5Cl2
Molecular Weight256.09
Purity98%
Density1.6±0.1 g/cm3
Boiling Point552.2±60.0 °C at 760 mmHg
Melting Point268-269°C
AppearanceWhite or colorless crystal or crystalline powder, odorless, slightly bitter
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 57381-26-7 |
| Catalog No. | 2A-9011031 |
| Chinese Name | 伊索拉定 |
| Synonyms | 2',5'-Dichlorobenzoguanamine; MFCD00866871; Irsogladin; 6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diamine; gaslon; Irsogladine; Dicloguamine |
| Molecular Formula | C9H7N5Cl2 |
| Molecular Weight | 256.09 |
| Purity | 98 |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 552.2±60.0 °C at 760 mmHg |
| Melting Point | 268-269°C |
| Appearance | White or colorless crystal or crystalline powder, odorless, slightly bitter |
| Storage Condition | -20°C |
| Packaging | III |
| Application | Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder. |
| HTC | 2942000000 |
| MDL Number | MFCD00866871 |
| SMILES | Nc1nc(N)nc(-c2cc(Cl)ccc2Cl)n1 |
| InChI | InChI=1S/C9H7Cl2N5.C4H4O4/c10-4-1-2-6(11)5(3-4)7-14-8(12)16-9(13)15-7;5-3(6)1-2-4(7)8/h1-3H,(H4,12,13,14,15,16);1-2H,(H,5,6)(H,7,8)/b;2-1- |
| InChI Key | ATCGGEJZONJOCL-UHFFFAOYSA-N |
| Hazard Symbols | 3 |
| MSDS | msds/11031_1_57381_26_7.pdf |
| Use of | Properties Name Irsogladine Synonym More Synonyms Irsogladine Biological Activity Related Catalog Signaling Pathways >> GPCR/G Protein >> mAChR Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Inflammation/Immunology References [1]. Ren, C.J., et al., Irsogladine maleate inhibits angiogenesis in wild-type and plasminogen activator-deficient mice. J Surg Res, 1998. 77(2): p. 126-31. [2]. Kawasaki, Y., et al., Irsogladine malate up-regulates gap junctional intercellular communication between pancreatic cancer cells via PKA pathway. Pancreas, 2002. 25(4): p. 373-7. [3]. Kyoi, T., et al., Phosphodiesterase inhibition by a gastroprotective agent irsogladine: preferential blockade of cAMP hydrolysis. Life Sci, 2004. 75(15): p. 1833-42. Chemical & Physical Properties Exact Mass 255.007858 PSA 90.71000 Index of Refraction 1.706 InChIKey ATCGGEJZONJOCL-UHFFFAOYSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : 1,3,5-Triazine-2,4-diamine, 6-(2,5-dichlorophenyl)- CAS REGISTRY NUMBER : 57381-26-7 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C9-H7-Cl2-N5 MOLECULAR WEIGHT : HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4657907 Safety Information Hazard Codes Xn,N Safety Phrases S24-S61 WGK Germany 2 RTECS WL5075900 Packaging Group III Hazard Class 3 HS Code 2942000000 |
| Transport Info | Product Name: Irsogladine |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Iprozilamine | 55477-19-5 | 2A-9011022 |
| Irgafen | 2A-302106 | 2A-9011023 |
| Irindalone | 96478-43-2 | 2A-9011024 |
| Irisquinone | 56495-82-0 | 2A-9011028 |
| Iroplakts | 154248-96-1 | 2A-9011030 |
| Irsogladine maleate | 84504-69-8 | 2A-9011032 |
| Isalsteine | 116818-99-6 | 2A-9011033 |
| Isamfazone | 55902-02-8 | 2A-9011034 |
| Isazophos | 42509-80-8 | 2A-9011035 |
| Isbogrel | 89667-40-3 | 2A-9011036 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS