| Chemical & Physical Properties | |
|---|---|
| CAS Number | 61890-25-3 |
| Catalog No. | 2A-0109620 |
| Chinese Name | 1-苯基-2-(吡啶-2-基)乙胺 |
| Synonyms | 1-phenyl-2-pyridin-2-yl-ethylamine; 2-aziridin-1-yl-1-phenyl-ethanol |
| Molecular Formula | C13H14N2 |
| Molecular Weight | 223.70 |
| Purity | 96+ |
| Appearance | solid |
| Application | (Rac)-Lanicemine ((Rac)-AZD6765) is the racemate of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA receptor antagonist with Ki of 0.56-2.1 μM. In CHO and Xenopus oocytes, the IC50 is 4-7 μM a |
| EINECS | 0 |
| HTC | 2933399090 |
| UN(IATA) | 0 |
| PubChem ID | 329776048 |
| MDL Number | MFCD09997610 |
| SMILES | NCCC1=CN(C2=CC=CC=C2)N=C1.[H]Cl |
| InChI | 1S/C11H13N3.ClH/c12-7-6-10-8-13-14(9-10)11-4-2-1-3-5-11;/h1-5,8-9H,6-7,12H2;1H |
| InChI Key | MZXINSJWQRZLQM-UHFFFAOYSA-N |
| NACRES Code | NA.21 |
| UNSPSC | 12352116 |
| MSDS | msds/109620_1_61890_25_3.pdf |
| Use of | (Rac)-Lanicemine ((Rac)-AZD6765) is the racemate of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects[1]. Properties Name 1-Phenyl-2-(2-pyridinyl)ethanamine Synonym More Synonyms (Rac)-Lanicemine Biological Activity Description (Rac)-Lanicemine ((Rac)-AZD6765) is the racemate of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects[1]. Related Catalog Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR NMDA receptor[1] References [1]. Sanacora G, et al. Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacywith minimal psychotomimetic adverse effects. Mol Psychiatry. 2014 Sep;19(9):978-85. Chemical & Physical Properties Molecular Formula C13H14N2 Exact Mass 198.11600 PSA 38.91000 LogP 3.02440 InChIKey FWUQWDCOOWEXRY-UHFFFAOYSA-N Safety Information HS Code 2933399090 Synthetic Route Total: 1 Page 1-phenyl-2-[2]p... CAS#:61890-12-8 (Rac)-Lanicemine CAS#:61890-25-3 Literature: Bower; Ramage Journal of the Chemical Society, 1957 , p. 4506,4509 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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