| Chemical & Physical Properties | |
|---|---|
| CAS Number | 86770-76-5 |
| Catalog No. | 2A-0109617 |
| Chinese Name | PEG4-苄醚 |
| Synonyms | 1-phenyl-2,5,8,11-tetraoxatridecan-13-amine |
| Molecular Formula | C15H25O4N1 |
| Molecular Weight | 283.37 |
| Purity | 96+ |
| Boiling Point | 390.4±32.0°C at 760 mmHg |
| Storage Condition | 2-8°C, protected from light, stored in inert gas |
| Application | Benzyl-PEG4-amine is a PROTAC linker, belonging to the PEG class. Can be used to synthesize PROTAC molecules. |
| EINECS | 0 |
| HTC | 2921499090 |
| UN(IATA) | 0 |
| MDL Number | MFCD21609490 |
| SMILES | NCCOCCOCCOCCOCc1ccccc1 |
| InChI Key | IYODTXXMZZZHEJ-UHFFFAOYSA-N |
| MSDS | msds/109617_1_86770_76_5.pdf |
| Bioactivity | Benzyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target PEGs In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Boiling Point 390.4±32.0°C at 760 mmHg Molecular Formula C15H25NO4 Molecular Weight 283.36300 Exact Mass 283.17800 PSA 62.94000 LogP 1.91200 InChIKey IYODTXXMZZZHEJ-UHFFFAOYSA-N SMILES NCCOCCOCCOCCOCc1ccccc1 |
| Use of | Benzyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Name 2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethanamine Synonym More Synonyms Benzyl-PEG4-amine Biological Activity Description Benzyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Molecular Formula C15H25NO4 Exact Mass 283.17800 PSA 62.94000 LogP 1.91200 InChIKey IYODTXXMZZZHEJ-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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