CAS Number80-13-7
SynonymsPantocide; Benzoesaeure-(sulfonsaeure-(4)-dichloramid); Gynamide; EINECS 201-253-1; Zeptabs; p-Dichlorsulfamid-benzoesaeure; Halazon; Pantosid; Pentocid; 4-dichlorosulfamoyl-benzoic acid; PANTOCID; 4-Dichlorsulfamoyl-benzoesaeure; Halozone; MFCD00045858; 4-[(dichloroamino)sulfonyl]-benzoic acid
Molecular FormulaC7H5Cl2NO4S
Molecular Weight270.09
Purity98.00%
Density1.717 g/cm3
Boiling Point437ºC at 760 mmHg
Melting Point213ºC
Appearancewhite powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 80-13-7 |
| Catalog No. | 2A-9010813 |
| Chinese Name | 哈拉宗 |
| Synonyms | Pantocide; Benzoesaeure-(sulfonsaeure-(4)-dichloramid); Gynamide; EINECS 201-253-1; Zeptabs; p-Dichlorsulfamid-benzoesaeure; Halazon; Pantosid; Pentocid; 4-dichlorosulfamoyl-benzoic acid; PANTOCID; 4-Dichlorsulfamoyl-benzoesaeure; Halozone; MFCD00045858; 4-[(dichloroamino)sulfonyl]-benzoic acid |
| Molecular Formula | C7H5Cl2NO4S |
| Molecular Weight | 270.09 |
| Purity | 98.00 |
| Density | 1.717 g/cm3 |
| Boiling Point | 437ºC at 760 mmHg |
| Melting Point | 213ºC |
| Appearance | white powder |
| Storage Condition | This product should be sealed and stored in a cool |
| Packaging | III |
| Application | Halazone is an atypical antibacterial sulfonamide derivative and a carbonic anhydrase II inhibitor with a Kd value of 1.45 µM. Halazone protects sodium channels from inactivation. Halazone is widely u |
| HTC | 2935009090 |
| MDL Number | C7H5Cl2NO4S |
| SMILES | O=C(O)c1ccc(S(=O)(=O)N(Cl)Cl)cc1 |
| InChI | InChI=1S/C7H5Cl2NO4S/c8-10(9)15(13,14)6-3-1-5(2-4-6)7(11)12/h1-4H,(H,11,12) |
| InChI Key | XPDVQPODLRGWPL-UHFFFAOYSA-N |
| Hazard Symbols | 5.1 |
| MSDS | msds/10813_1_80_13_7.pdf |
| Bioactivity | Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a Kd value of 1.45 µM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water[1][2]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase Signaling Pathways >> Anti-infection >> Bacterial In Vitro Halazone is chemically closely related to Chloramine-T, the nitrogen atom is linked with two instead of one chlorine atom and, certainly more important here, a methyl group is replaced by a carboxyl group. The effect of Halazone on the sodium current is studied in voltage-clamped single nerve fibers of the frog. The oxidant Halazone drastically inhibits inactivation[1]. References [1]. M Rack, et al. Effects of Some Chemical Reagents on Sodium Current Inactivation in Myelinated Nerve Fibers of the Frog. Biophys J. 1986 Oct;50(4):557-64. [2]. Rema Iyer, et al. Inhibition Profiling of Human Carbonic Anhydrase II by High-Throughput Screening of Structurally Diverse, Biologically Active Compounds. J Biomol Screen. 2006 Oct;11(7):782-91. Chemical & Physical Properties Density 1.717 g/cm3 Boiling Point 437ºC at 760 mmHg Melting Point 213ºC Molecular Formula C7H5Cl2NO4S Molecular Weight 270.09000 Flash Point 218.1ºC Exact Mass 268.93200 PSA 83.06000 LogP 2.76390 InChIKey XPDVQPODLRGWPL-UHFFFAOYSA-N SMILES O=C(O)c1ccc(S(=O)(=O)N(Cl)Cl)cc1 Stability Stable, but may be light sensitive. Incompatible with strong oxidizing agents. |
| Use of | Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a Kd value of 1.45 µM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water[1][2]. Properties Name Halazone Synonym More Synonyms halazone Biological Activity Description Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a Kd value of 1.45 µM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water[1][2]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase Signaling Pathways >> Anti-infection >> Bacterial In Vitro Halazone is chemically closely related to Chloramine-T, the nitrogen atom is linked with two instead of one chlorine atom and, certainly more important here, a methyl group is replaced by a carboxyl group. The effect of Halazone on the sodium current is studied in voltage-clamped single nerve fibers of the frog. The oxidant Halazone drastically inhibits inactivation[1]. References [1]. M Rack, et al. Effects of Some Chemical Reagents on Sodium Current Inactivation in Myelinated Nerve Fibers of the Frog. Biophys J. 1986 Oct;50(4):557-64. [2]. Rema Iyer, et al. Inhibition Profiling of Human Carbonic Anhydrase II by High-Throughput Screening of Structurally Diverse, Biologically Active Compounds. J Biomol Screen. 2006 Oct;11(7):782-91. Chemical & Physical Properties Exact Mass 268.93200 PSA 83.06000 LogP 2.76390 InChIKey XPDVQPODLRGWPL-UHFFFAOYSA-N Stability Stable, but may be light sensitive. Incompatible with strong oxidizing agents. |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 35.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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