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Ginkgolide J structure, CAS 107438-79-9

Ginkgolide J

CAS Number107438-79-9

SynonymsGinkgolideJ; Ginkgolid J; 7beta-hydroxyginkgolide a

Molecular FormulaC20H24O10

Molecular Weight424.4

Purity98%

Density1.6±0.1 g/cm3

Boiling Point760.4±60.0 °C at 760 mmHg

Melting Point41-42 °C

Flash Point

AppearanceWhite crystal

EINECS

MSDSChineseEnglish

SymbolTransport

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Cat. No.: 2A-9010729 Purity: 98%
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Quality Control of [ 107438-79-9 ] Purity: 98% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number107438-79-9
Catalog No.2A-9010729
Chinese Name银杏内酯J
SynonymsGinkgolideJ; Ginkgolid J; 7beta-hydroxyginkgolide a
Molecular FormulaC20H24O10
Molecular Weight424.4
Purity98
Density1.6±0.1 g/cm3
Boiling Point760.4±60.0 °C at 760 mmHg
Melting Point41-42 °C
AppearanceWhite crystal
Storage Condition2-8°C, protected from light
ApplicationGinkgolide J is the main component of the non-flavonoid fraction of Ginkgo biloba leaves, with an IC50 ranging from 12-54 µM. It has neuroprotective and anti-neuronal apoptosis capabilities.
MDL NumberMFCD03093737
SMILESCC1C(=O)OC2CC34C5OC(=O)C3(OC3OC(=O)C(O)C34C(C(C)(C)C)C5O)C21O
InChI KeyLMEHVEUFNRJAAV-UKWFQYJJSA-N
Hazard SymbolsTransport
MSDSmsds/10729_1_107438_79_9.pdf
BioactivityGinkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 µM, has neuroprotective and anti neuronal apoptotic ability[1][2]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis In Vivo Ginkgolide J (100 μM) treatment reduces the apoptotic damage induced by serum deprivation (24h) or treatment with Staurosporine (200 nM, 24h) in cultured chick embryonic neurons[1]. References [1]. Ahlemeyer B, et al. Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease. Pharmacopsychiatry. 2003 Jun; 36 Suppl 1:S8-14. [2]. Sylvia Pietri, et al. Synthesis and Biological Studies of a New Ginkgolide C Derivative: Evidence That the Cardioprotective Effect of Ginkgolides Is Unrelated to PAF Inhibition. DRUG DEVELOPMENT RESEARCH. 2001.54:191-201. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Boiling Point 760.4±60.0 °C at 760 mmHg Melting Point 41-42 °C Molecular Formula C20H24O10 Molecular Weight 424.399 Flash Point 273.6±26.4 °C Exact Mass 424.136932 PSA 148.82000 LogP -0.68 Vapour Pressure 0.0±5.8 mmHg at 25°C Index of Refraction 1.651 InChIKey LMEHVEUFNRJAAV-UKWFQYJJSA-N SMILES CC1C(=O)OC2CC34C5OC(=O)C3(OC3OC(=O)C(O)C34C(C(C)(C)C)C5O)C21O
Use ofGinkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 µM, has neuroprotective and anti neuronal apoptotic ability[1][2]. Properties Articles11 Name Ginkgolide J Synonym More Synonyms Ginkgolide J Biological Activity Description Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 µM, has neuroprotective and anti neuronal apoptotic ability[1][2]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis In Vivo Ginkgolide J (100 μM) treatment reduces the apoptotic damage induced by serum deprivation (24h) or treatment with Staurosporine (200 nM, 24h) in cultured chick embryonic neurons[1]. References [1]. Ahlemeyer B, et al. Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease. Pharmacopsychiatry. 2003 Jun; 36 Suppl 1:S8-14. [2]. Sylvia Pietri, et al. Synthesis and Biological Studies of a New Ginkgolide C Derivative: Evidence That the Cardioprotective Effect of Ginkgolides Is Unrelated to PAF Inhibition. DRUG DEVELOPMENT RESEARCH. 2001.54:191-201. Chemical & Physical Properties Molecular Formula C20H24O10 Exact Mass 424.136932 PSA 148.82000 LogP -0.68 Index of Refraction 1.651 InChIKey LMEHVEUFNRJAAV-UKWFQYJJSA-N
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
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