CAS Number67469-57-2
Synonyms1-[2-(Diphenylmethoxy)ethyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine dihydrochloride; 1-[2-(Diphenylmethoxy)ethyl]-4-[(2E)-3-phenyl-2-propen-1-yl]piperazine dihydrochloride; Piperazine, 1-[2-(diphenylmethoxy)ethyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride (1:2)
Molecular FormulaC36H39N5O
Molecular Weight557.745
Purity96+%
Density1.085 g/cm3
Boiling Point550.5ºC at 760 mmHg
EINECS0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 67469-57-2 |
| Catalog No. | 2A-0104219 |
| Chinese Name | 1-[2-(二苯基甲氧基)乙基]-4-(3-苯基-2-丙苯基)-哌嗪 |
| Synonyms | 1-[2-(Diphenylmethoxy)ethyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine dihydrochloride; 1-[2-(Diphenylmethoxy)ethyl]-4-[(2E)-3-phenyl-2-propen-1-yl]piperazine dihydrochloride; Piperazine, 1-[2-(diphenylmethoxy)ethyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride (1:2) |
| Molecular Formula | C36H39N5O |
| Molecular Weight | 557.745 |
| Purity | 96+ |
| Density | 1.085 g/cm3 |
| Boiling Point | 550.5ºC at 760 mmHg |
| Storage Condition | -20°C |
| Application | GBR 12783 is a specific, potent and selective dopamine uptake inhibitor that inhibits [3H]dopamine uptake by rat and mouse striatal synaptosomes with IC50 of 1.8 nM and 1.2 nM respectively. GBR 12783 |
| EINECS | 0 |
| HTC | 2933599090 |
| UN(IATA) | 0 |
| MDL Number | MFCD03304072 |
| SMILES | C(=Cc1ccccc1)CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1 |
| InChI | InChI=1S/C28H32N2O/c1-4-11-25(12-5-1)13-10-18-29-19-21-30(22-20-29)23-24-31-28(26-14-6-2-7-15-26)27-16-8-3-9-17-27/h1-17,28H,18-24H2/b13-10+ |
| InChI Key | XFBDGHFDKJITGC-JLHYYAGUSA-N |
| MSDS | msds/104219_1_67469_57_2.pdf |
| Use of | Properties Name 1-(2-benzhydryloxyethyl)-4-(3-phenylprop-2-enyl)piperazine,dihydrochloride Synonym More Synonyms GBR 12783 dihydrochloride Biological Activity Related Catalog Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease References [1]. Nail-Boucherie K, et al. The specific dopamine uptake inhibitor GBR 12783 improves learning of inhibitory avoidance and increases hippocampal acetylcholine release. Brain Res Cogn Brain Res. 1998 Oct;7(2):203-5. [2]. Bonnet JJ, et al. GBR 12783, a potent and selective inhibitor of dopamine uptake: biochemical studies in vivo and ex vivo. Eur J Pharmacol. 1986 Feb 18;121(2):199-209. Chemical & Physical Properties Molecular Formula C28H32N2O Exact Mass 484.204834 PSA 15.71000 LogP 6.60340 Index of Refraction 1.601 InChIKey XFBDGHFDKJITGC-JLHYYAGUSA-N Safety Information HS Code 2933599090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Related Products in Heterocyclic Building Blocks | ||
|---|---|---|
| 1-(2-(4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOXY)ETHYL)-1H-1,2,3-TRIAZOLE-4-CARBOTHIALDEHYDE | 957120-67-1 | 2A-0104206 |
| 1-(2-(4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOXY)ETHYL)-1H-PYRAZOLE | 957061-20-0 | 2A-0104207 |
| 1-(2-(4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOXY)ETHYL)PIPERIDINE | 934586-49-9 | 2A-0104208 |
| 1-(2-(4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOXY)ETHYL)PYRROLIDINE | 656257-46-4 | 2A-0104209 |
| 1-(2-(4-METHOXYPHENYL)-2-(3-(4-METHOXYPHENYL)PROPOXY)ETHYL)-1H-IMIDAZOLE HYDROCHLORIDE | 130495-35-1 | 2A-0104215 |
| 1-(2-(FURAN-2-YL)-4-MERCAPTO-6-METHYLPYRIMIDIN-5-YL)ETHANONE | 13995-71-6 | 2A-0104227 |
| 1-(2-AMINO-2-OXOETHYL)PIPERIDINE-4-CARBOXYLIC ACID | 1155502-40-1 | 2A-0104268 |
| 1-(2-AMINOETHYL)-1H-PYRROLE-2,5-DIONE HYDROCHLORIDE | 134272-64-3 | 2A-0201950 |
| 1-(2-BENZYLPHENYL)-4-METHYLPIPERAZINE | 131635-06-8 | 2A-0104325 |
| 1-(2-BROMO-5-CHLOROPHENYL)-4-METHYLPIPERAZINE | 1261940-25-3 | 2A-0104336 |
| Browse all Heterocyclic Building Blocks products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS