CAS Number545-48-2
SynonymsHOMOOLESTRANOL; olean-12-ene-3,28-diol; MFCD00017294; Erythrodiol; (3β)-Olean-12-ene-3,28-diol; EINECS 208-890-4; Olean-12-ene-3β,28-diol; 12-OLEANENE-3,28-DIOL; (3β)-Olean-12-ène-3,28-diol; ERYTHODIOL; Oleanolic alcohol
Molecular FormulaC30H50O2
Molecular Weight442.72
Purity≥90.0 (GC)%
Density1.1±0.1 g/cm3
Boiling Point520.5±50.0 °C at 760 mmHg
Melting Point230-231 °C (lit.)
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 545-48-2 |
| Catalog No. | 2A-9010370 |
| Chinese Name | 古柯二醇 |
| Synonyms | HOMOOLESTRANOL; olean-12-ene-3,28-diol; MFCD00017294; Erythrodiol; (3β)-Olean-12-ene-3,28-diol; EINECS 208-890-4; Olean-12-ene-3β,28-diol; 12-OLEANENE-3,28-DIOL; (3β)-Olean-12-ène-3,28-diol; ERYTHODIOL; Oleanolic alcohol |
| Molecular Formula | C30H50O2 |
| Molecular Weight | 442.72 |
| Purity | ≥90.0 (GC) |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 520.5±50.0 °C at 760 mmHg |
| Melting Point | 230-231 °C (lit.) |
| Appearance | powder |
| Storage Condition | 2-8℃, dry, sealed |
| Application | Erythrodiol is a component of olive oil. Erythrodiol promotes (ChE) by selectively inhibiting the degradation of ABCA1 protein. Erythrodiol is a good candidate for treating or preventing atheroscleros |
| MDL Number | MFCD00017294 |
| SMILES | [H][C@@]12CC(C)(C)CC[C@]1(CO)CC[C@]3(C)C2=CC[C@]4([H])[C@@]5(C)CC[C@H](O)C(C)(C)[C@]5([H])CC[C@@]34C |
| InChI | 1S/C30H50O2/c1-25(2)14-16-30(19-31)17-15-28(6)20(21(30)18-25)8-9-23-27(5)12-11-24(32)26(3,4)22(27)10-13-29(23,28)7/h8,21-24,31-32H,9-19H2,1-7H3/t21-,22-,23+,24-,27-,28+,29+,30+/m0/s1 |
| InChI Key | PSZDOEIIIJFCFE-OSQDELBUSA-N |
| Beilstein/REAXYS | 2340203 |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/10370_1_545_48_2.pdf |
| Bioactivity | Erythrodiol is an olive oil component. Erythrodiol promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein. Erythrodiol is a good candidate to be further explored for therapeutic or preventive application in the context of atherosclerosis[1]. Related Catalog Research Areas >> Metabolic Disease In Vitro Erythrodiol (1-15 μM; 24 hours) enhances ABCA1 protein level in a concentration-dependent manner, and reachs significance at 10 and 15 μM[1]. Western Blot Analysis[1] Cell Line: THP-1 macrophage cells Concentration: 1 μM, 2.5 μM, 5 μM, 10 μM, and 15 μM Incubation Time: 24 hours Result: Increased ABCA1 protein expression. References [1]. Wang L, et al. Erythrodiol, an Olive Oil Constituent, Increases the Half-Life of ABCA1 and Enhances Cholesterol Efflux from THP-1-Derived Macrophages. Front Pharmacol. 2017 Jun 13;8:375. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 520.5±50.0 °C at 760 mmHg Melting Point 230-231ºC(lit.) Molecular Formula C30H50O2 Molecular Weight 442.717 Flash Point 209.9±24.7 °C Exact Mass 442.381073 PSA 40.46000 LogP 9.18 Vapour Pressure 0.0±3.1 mmHg at 25°C Index of Refraction 1.551 InChIKey PSZDOEIIIJFCFE-OSQDELBUSA-N SMILES CC1(C)CCC2(CO)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1 |
| Use of | Erythrodiol is an olive oil component. Erythrodiol promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein. Erythrodiol is a good candidate to be further explored for therapeutic or preventive application in the context of atherosclerosis[1]. Properties Articles22 Name erythrodiol Synonym More Synonyms Erythrodiol Biological Activity Description Erythrodiol is an olive oil component. Erythrodiol promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein. Erythrodiol is a good candidate to be further explored for therapeutic or preventive application in the context of atherosclerosis[1]. Related Catalog Research Areas >> Metabolic Disease References [1]. Wang L, et al. Erythrodiol, an Olive Oil Constituent, Increases the Half-Life of ABCA1 and Enhances Cholesterol Efflux from THP-1-Derived Macrophages. Front Pharmacol. 2017 Jun 13;8:375. Chemical & Physical Properties Molecular Formula C30H50O2 Exact Mass 442.381073 PSA 40.46000 Index of Refraction 1.551 InChIKey PSZDOEIIIJFCFE-OSQDELBUSA-N |
| Transport Info | Product name: Purity: 97.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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