
CAS Number146665-77-2
Synonyms(SP-4-2)-[(4R,5R)-2-Isopropyl-1,3-dioxolane-4,5; Platinum(2+) malonate [(4R,5R)-2-isopropyl-1,3-dioxolane-4,5-diyl]dimethanamine (1:1:1); EPTAPLATIN,SUNPLA; SKI 2053R; [Malonato(2-)-κO,O]platinum - [(4R,5R)-2-isopropyl-1,3-dioxolane-4,5-diyl]dimethanamine (1:1); sunpla; EPOXYPROGESTERONE; Heptaplatin; cis-[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane](malonate)platinum(II)
Molecular FormulaC11H20N2O6Pt
Molecular Weight471.36
Purity98%
Boiling Point261.5ºC at 760 mmHg
Melting Point43-49ºC
AppearanceWhite crystalline powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 146665-77-2 |
| Catalog No. | 2A-9010357 |
| Chinese Name | 依铂(SKI-2053R) |
| Synonyms | (SP-4-2)-[(4R,5R)-2-Isopropyl-1,3-dioxolane-4,5; Platinum(2+) malonate [(4R,5R)-2-isopropyl-1,3-dioxolane-4,5-diyl]dimethanamine (1:1:1); EPTAPLATIN,SUNPLA; SKI 2053R; [Malonato(2-)-κO,O]platinum - [(4R,5R)-2-isopropyl-1,3-dioxolane-4,5-diyl]dimethanamine (1:1); sunpla; EPOXYPROGESTERONE; Heptaplatin; cis-[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane](malonate)platinum(II) |
| Molecular Formula | C11H20N2O6Pt |
| Molecular Weight | 471.36 |
| Purity | 98 |
| Boiling Point | 261.5ºC at 760 mmHg |
| Melting Point | 43-49ºC |
| Appearance | White crystalline powder |
| Storage Condition | 2-8°C, protected from light, stored under inert ga |
| Application | Seven platinum (SKI 2053R) is a platinum derivative with anticancer activity against a variety of cancer cell lines, including cisplatin-resistant tumor cell lines. SKI-2053R is very active in gastric |
| SMILES | [Pt++].CC(C)C1O[C@H](CN)[C@@H](CN)O1.[O-]C(=O)CC([O-])=O |
| InChI | InChI=1S/C8H18N2O2.C3H4O4.Pt/c1-5(2)8-11-6(3-9)7(4-10)12-8;4-2(5)1-3(6)7;/h5-8H,3-4,9-10H2,1-2H3;1H2,(H,4,5)(H,6,7);/q;;+2/p-2/t6-,7-;;/m1../s1 |
| InChI Key | InChIKey=XJXKGUZINMNEDK-GPJOBVNKSA-L |
| Transport Info | Product name: SKI-2053R |
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