CAS Number24169-02-6
SynonymsSalpetersäure--1-{2-[(4-chlorbenzyl)oxy]-2-(2,4-dichlorphenyl)ethyl}-1H-imidazol(1:1); EINECS 246-053-5; R 14827 {Nitrate}; UNII:H438WYN10E; Econazole nitrate; 1-{2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate; 1-{2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophényl)éthyl}-1H-imidazole nitrate; Econazole nitrate salt; 1-{2-[(4-Chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate (1:1); 1-[2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate; 1H-Imidazole, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl]ethyl)-, nitrate; 1-(2-[(4-Chlorophenyl)methoxy]-2-[2,4-dichlorophenyl]ethyl)-1H-imidazole; 1H-Imidazole, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-, nitrate (1:1); MFCD00058160; 1-[2-(4-Chlorobenzyloxy)-2-(2,4-di
Molecular FormulaC18H16Cl3N3O4
Molecular Weight444.70
Purity99%
Melting Point162°C
Appearancepowder or crystals
EINECS246-053-5
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 24169-02-6 |
| Catalog No. | 2A-9010279 |
| Chinese Name | 硝酸益康唑 |
| Synonyms | Salpetersäure--1-{2-[(4-chlorbenzyl)oxy]-2-(2,4-dichlorphenyl)ethyl}-1H-imidazol(1:1); EINECS 246-053-5; R 14827 {Nitrate}; UNII:H438WYN10E; Econazole nitrate; 1-{2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate; 1-{2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophényl)éthyl}-1H-imidazole nitrate; Econazole nitrate salt; 1-{2-[(4-Chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate (1:1); 1-[2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate; 1H-Imidazole, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl]ethyl)-, nitrate; 1-(2-[(4-Chlorophenyl)methoxy]-2-[2,4-dichlorophenyl]ethyl)-1H-imidazole; 1H-Imidazole, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-, nitrate (1:1); MFCD00058160; 1-[2-(4-Chlorobenzyloxy)-2-(2,4-di |
| Molecular Formula | C18H16Cl3N3O4 |
| Molecular Weight | 444.70 |
| Purity | 99 |
| Melting Point | 162°C |
| Appearance | powder or crystals |
| Water Solubility | <0.1 g/100 mL at 19 ºC |
| Storage Condition | Store in a compact container in a cool, dry place |
| Application | Econazole (Spectazole) nitrate is an imidazole antifungal compound. |
| EINECS | 246-053-5 |
| HTC | 2933290090 |
| PubChem ID | 24894567 |
| MDL Number | MFCD00058160 |
| SMILES | O[N+]([O-])=O.Clc1ccc(COC(Cn2ccnc2)c3ccc(Cl)cc3Cl)cc1 |
| InChI | 1S/C18H15Cl3N2O.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4) |
| InChI Key | DDXORDQKGIZAME-UHFFFAOYSA-N |
| NACRES Code | NA.85 |
| UNSPSC | 51102829 |
| Hazard Symbols | Transport |
| MSDS | msds/10279_1_24169_02_6.pdf |
| Bioactivity | Econazole nitrate (Spectazole) is an imidazole class antifungal medication.Target: AntifungalEconazole nitrate is an antifungal medication of the imidazole class. It is used as a cream to treat skin infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch. In each of these tests the activity of econazole was compared with that of different reference drugs. Vaginal candidiasis in rats was cured after oral administration of econazole. Toxicity and teratogenicity studies in different laboratory animals indicate that econazole is well tolerated [1]. Related Catalog Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Infection References [1]. Thienpont, D., et al., Bilogical and toxicological properties of econazole, a broad-spectrum antimycotic. Arzneimittelforschung, 1975. 25(2): p. 224-30. Chemical & Physical Properties Melting Point 162°C Molecular Formula C18H16Cl3N3O4 Molecular Weight 444.696 Exact Mass 443.020630 PSA 93.10000 LogP 5.97690 InChIKey DDXORDQKGIZAME-UHFFFAOYSA-N SMILES Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1.O=[N+]([O-])O Water Solubility <0.1 g/100 mL at 19 ºC |
| Use of | Econazole nitrate (Spectazole) is an imidazole class antifungal medication.Target: AntifungalEconazole nitrate is an antifungal medication of the imidazole class. It is used as a cream to treat skin infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch. In each of these tests the activity of econazole was compared with that of different reference drugs. Vaginal candidiasis in rats was cured after oral administration of econazole. Toxicity and teratogenicity studies in different laboratory animals indicate that econazole is well tolerated [1]. Properties Name Econazole Nitrate Synonym More Synonyms Econazole (nitrate) Biological Activity Description Econazole nitrate (Spectazole) is an imidazole class antifungal medication.Target: AntifungalEconazole nitrate is an antifungal medication of the imidazole class. It is used as a cream to treat skin infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch. In each of these tests the activity of econazole was compared with that of different reference drugs. Vaginal candidiasis in rats was cured after oral administration of econazole. Toxicity and teratogenicity studies in different laboratory animals indicate that econazole is well tolerated [1]. Related Catalog Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Infection References [1]. Thienpont, D., et al., Bilogical and toxicological properties of econazole, a broad-spectrum antimycotic. Arzneimittelforschung, 1975. 25(2): p. 224-30. Chemical & Physical Properties Exact Mass 443.020630 PSA 93.10000 LogP 5.97690 InChIKey DDXORDQKGIZAME-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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