CAS Number132173-07-0
Synonyms(Z)-N-(3-(3-Chloro-4-cyclohexylphenyl)allyl)-N-ethylcyclohexanamine hydrochloride; (Z)-N-(3-(3-Chloro-4-cyclohexylphenyl)-2-propenyl)-N-ethylcyclohexanamine hydrochloride
Molecular FormulaC23H35Cl2N
Molecular Weight396.43700
Purity96+%
Boiling Point479.9ºC at 760 mmHg
EINECS0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 132173-07-0 |
| Catalog No. | 2A-0102500 |
| Chinese Name | 3-(3-氯-4-环己基苯基)-N-环己基-N-乙基-2(Z)-丙烯基胺 |
| Synonyms | (Z)-N-(3-(3-Chloro-4-cyclohexylphenyl)allyl)-N-ethylcyclohexanamine hydrochloride; (Z)-N-(3-(3-Chloro-4-cyclohexylphenyl)-2-propenyl)-N-ethylcyclohexanamine hydrochloride |
| Molecular Formula | C23H35Cl2N |
| Molecular Weight | 396.43700 |
| Purity | 96+ |
| Boiling Point | 479.9ºC at 760 mmHg |
| Storage Condition | 2-8°C |
| Application | SR-31747 is a sigma ligand with immunosuppressive and anti-inflammatory properties. SR-31747 prevents cell proliferation by inhibiting sterol isomerase. |
| EINECS | 0 |
| HTC | 2921499090 |
| UN(IATA) | 0 |
| SMILES | CCN(CC=Cc1ccc(C2CCCCC2)c(Cl)c1)C1CCCCC1.Cl |
| InChI | InChI=1S/C23H34ClN.ClH/c1-2-25(21-13-7-4-8-14-21)17-9-10-19-15-16-22(23(24)18-19)20-11-5-3-6-12-20;/h9-10,15-16,18,20-21H,2-8,11-14,17H2,1H3;1H/b10-9-; |
| InChI Key | HKHPCMBPASXYGP-KVVVOXFISA-N |
| Use of | SR-31747 is a sigma ligand with immunosuppressive and anti-inflammatory properties. SR-31747 blocks cell proliferation by inhibiting sterol isomerase[1][2]. Properties Name N-[(Z)-3-(3-chloro-4-cyclohexylphenyl)prop-2-enyl]-N-ethylcyclohexanamine,hydrochloride Synonym More Synonyms SR-31747 Biological Activity Description SR-31747 is a sigma ligand with immunosuppressive and anti-inflammatory properties. SR-31747 blocks cell proliferation by inhibiting sterol isomerase[1][2]. Related Catalog Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Sigma Receptor Sigma ligand[1] In Vitro SR-31747 blocks the proliferation of lymphocytes at a concentration of 10 nM. SR-31747 is capable of inhibiting T-cell proliferation when added as late as 24 h after activation. SR-31747 arrests proliferation in yeast cells in a dose-dependent manner[2]. References [1]. Derocq JM, et al. In vivo inhibition of endotoxin-induced pro-inflammatory cytokines production by the sigma ligand SR 31747. J Pharmacol Exp Ther. 1995 Jan;272(1):224-30. [2]. Silve S, et al. The immunosuppressant SR 31747 blocks cell proliferation by inhibiting a steroid isomerase in Saccharomyces cerevisiae. Mol Cell Biol. 1996 Jun;16(6):2719-27. Chemical & Physical Properties Exact Mass 395.21500 PSA 3.24000 LogP 7.85750 InChIKey HKHPCMBPASXYGP-KVVVOXFISA-N Safety Information HS Code 2921499090 |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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