CAS Number52365-63-6
SynonymsDipivefrina; [2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate; AKPro; Dipivefrine; Dipivefrinum; Dipivefrina [INN-Spanish]; Dipivefrinum [INN-Latin]; Dipivefrin [USAN]; dipivalyl epinephrine; Propine
Molecular FormulaC19H29NO5
Molecular Weight387.90
Purity99%
Density1.097 g/cm3
Boiling Point473.7ºC at 760 mmHg
Melting Point146-147°
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 52365-63-6 |
| Catalog No. | 2A-9010197 |
| Chinese Name | 地匹福林 |
| Synonyms | Dipivefrina; [2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate; AKPro; Dipivefrine; Dipivefrinum; Dipivefrina [INN-Spanish]; Dipivefrinum [INN-Latin]; Dipivefrin [USAN]; dipivalyl epinephrine; Propine |
| Molecular Formula | C19H29NO5 |
| Molecular Weight | 387.90 |
| Purity | 99 |
| Density | 1.097 g/cm3 |
| Boiling Point | 473.7ºC at 760 mmHg |
| Melting Point | 146-147° |
| Application | Dipefoline is a potent adrenergic agonist. Dipivefrin is an adrenergic prodrug. Dipefoline can be used to reduce intraocular pressure in patients with chronic open-angle glaucoma [1][2]. |
| HTC | 2922509090 |
| SMILES | [Cl-].[N+H2](CC(O)c1cc(c(cc1)OC(=O)C(C)(C)C)OC(=O)C(C)(C)C)C |
| InChI | 1S/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H |
| InChI Key | VKFAUCPBMAGVRG-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/10197_1_52365_63_6.pdf |
| Use of | Dipivefrin is a potent adrenergic agonist. Dipivefrin is an adrenergic pro-drug. Dipivefrin can be used for reduce IOP (intraocular pressure) in patients suffering from chronic open angle glaucoma[1][2]. Properties Name dipivefrin Synonym More Synonyms Dipivefrin Biological Activity Description Dipivefrin is a potent adrenergic agonist. Dipivefrin is an adrenergic pro-drug. Dipivefrin can be used for reduce IOP (intraocular pressure) in patients suffering from chronic open angle glaucoma[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Human Endogenous Metabolite References [1]. Kass MA,et al. Dipivefrin and epinephrine treatment of elevated intraocular pressure: a comparative study. Arch Ophthalmol. 1979 Oct;97(10):1865-6. [2]. Alkholief M, et al. Thermoresponsive sol-gel improves ocular bioavailability of Dipivefrin hydrochloride and potentially reduces the elevated intraocular pressure in vivo. Saudi Pharm J. 2020 Aug;28(8):1019-1029. Chemical & Physical Properties Molecular Formula C19H29NO5 Exact Mass 351.20500 PSA 84.86000 LogP 3.23330 Index of Refraction 1.511 InChIKey OCUJLLGVOUDECM-UHFFFAOYSA-N Safety Information HS Code 2922509090 |
| Tax Rebate | 13.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Hygiene supervision and inspection of imported food S. Hygiene supervision and inspection of exported food |
| Transport Info | Product name: Supervision conditions A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
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