CAS Number137361-05-8
SynonymsN-(N'-Propylcarbamimidoyl)-L-ornithine; 3AR; Tocris-1200; MFCD01320455
Molecular FormulaC9H20N4O2
Molecular Weight380.40
Purity≥97.0 (HPLC)%
Density1.2±0.1 g/cm3
Boiling Point411.0±55.0 °C at 760 mmHg
Melting Point122 °C(lit.)
Appearancepowder
EINECS0
Symbol
Signal WordWarning
Please Login or Create an Account to: See VlP prices and availability
US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 137361-05-8 |
| Catalog No. | 2A-0101308 |
| Chinese Name | N-ω-丙基-L-精氨酸 |
| Synonyms | N-(N'-Propylcarbamimidoyl)-L-ornithine; 3AR; Tocris-1200; MFCD01320455 |
| Molecular Formula | C9H20N4O2 |
| Molecular Weight | 380.40 |
| Purity | ≥97.0 (HPLC) |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 411.0±55.0 °C at 760 mmHg |
| Melting Point | 122 °C(lit.) |
| Appearance | powder |
| Storage Condition | Sealed in a cool, dry environment |
| Packaging | II |
| Application | Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) is a highly efficient, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS) with a Ki of 57 nM. Nω-Propyl-L-arginine is |
| EINECS | 0 |
| HTC | 2925290090 |
| UN(IATA) | 0 |
| PubChem ID | 329763270 |
| MDL Number | MFCD11052921 |
| SMILES | OC(=O)[C@H](CCCN=[N+]=[N-])NC(=O)OCC1c2ccccc2-c3ccccc13 |
| InChI | 1S/C20H20N4O4/c21-24-22-11-5-10-18(19(25)26)23-20(27)28-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-4,6-9,17-18H,5,10-12H2,(H,23,27)(H,25,26)/t18-/m0/s1 |
| InChI Key | TVPIDQLSARDIPX-SFHVURJKSA-N |
| NACRES Code | NA.26 |
| UNSPSC | 12352209 |
| Hazard Symbols | 5.1 |
| MSDS | msds/101308_1_137361_05_8.pdf |
| Use of | Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS)[1][2]. Properties Name (2S)-2-amino-5-[(N'-propylcarbamimidoyl)amino]pentanoic acid Synonym More Synonyms Nω-Propyl-L-arginine Biological Activity Description Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS)[1][2]. Related Catalog Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Neurological Disease References [1]. Zhang HQ, et al. Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine. J Med Chem. 1997 Nov 21;40(24):3869-70. [2]. Klamer D, et al. The neuronal selective nitric oxide synthase inhibitor, Nomega-propyl-L-arginine, blocks the effects of phencyclidine on prepulse inhibition and locomotor activity in mice. Eur J Pharmacol. 2004 Oct 25;503(1-3):103-7. Chemical & Physical Properties Molecular Formula C9H20N4O2 Exact Mass 216.158630 PSA 111.23000 Index of Refraction 1.550 InChIKey AOMXURITGZJPKB-ZETCQYMHSA-N SMILES CCCN=C(N)NCCCC(N)C(=O)O Storage condition Desiccate at RT Safety Information Hazard Codes C,O WGK Germany 3 Packaging Group II Hazard Class 5.1 HS Code 2925290090 |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Summary 2925290090 other imines and their derivatives; salts thereof. Supervision conditions:None. VAT: 17.0%. Tax rebate rate:9.0%. MFN tariff: 6.5%. General tariff:30.0% |
| Related Products in Pharmaceutical Intermediates | ||
|---|---|---|
| (S)-2-AMINO-4-(((S)-1-CARBOXY-2-PHENYLETHYL)AMINO)-4-OXOBUTANOIC ACID | 13433-10-8 | 2A-0101294 |
| (S)-2-AMINO-4-((3-CARBOXYPROPANOYL)OXY)BUTANOIC ACID | 1492-23-5 | 2A-0101295 |
| (S)-2-AMINO-4-(2-FORMAMIDOPHENYL)-4-OXOBUTANOIC ACID | 3978-11-8 | 2A-0101296 |
| (S)-2-AMINO-4-BROMOBUTANOIC ACID HYDROCHLORIDE | 1187453-22-0 | 2A-0101302 |
| (S)-2-AMINO-4-METHYL-N-(4-NITROPHENYL)PENTANAMIDE HYDROCHLORIDE | 16010-98-3 | 2A-0101305 |
| (S)-2-AMINO-6-(2-HYDROXYPROPANOYL)-7,8-DIHYDROPTERIDIN-4(3H)-ONE | 17094-01-8 | 2A-1101314 |
| (S)-2-AMINO-6-HYDROXYHEXANOIC ACID | 6033-32-5 | 2A-1101315 |
| (S)-2-AMINO-8-(TERT-BUTOXY)-8-OXOOCTANOIC ACID | 276869-42-2 | 2A-0101317 |
| (S)-2-AMINO-N-((S)-1-AMINO-1-OXO-3-PHENYLPROPAN-2-YL)-3-METHYLBUTANAMIDE HYDROCHLORIDE | 129678-27-9 | 2A-0101318 |
| (S)-2-AMINO-N-((S)-3-METHYL-2-OXO-2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPIN-1-YL)PROPANAMIDE | 253136-72-0 | 2A-0101319 |
| Browse all Pharmaceutical Intermediates products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS