CAS Number17355-10-1
SynonymsN-L-Tyrosyl-L-leucin; TYR-LEU; L-Leucine,N-L-tyrosyl; N-L-tyrosyl-L-leucine; tyrosylleucine; L-Tyrosyl-L-leucine; L-Tyrosyl-L-leucin; H-TYR-LEU-OH; L-tyrosine-L-leucine; TYR-LEU CRYSTALLINE
Molecular FormulaC15H22N2O4
Molecular Weight196.63
Purity96+%
Density1.218g/cm3
Boiling Point575.9ºC at 760 mmHg
Appearancepowder
EINECS0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 17355-10-1 |
| Catalog No. | 2A-0101025 |
| Chinese Name | (S)-2-((S)-2-氨基-3-(4-羟基苯基)丙酰胺)-4-甲基戊酸 |
| Synonyms | N-L-Tyrosyl-L-leucin; TYR-LEU; L-Leucine,N-L-tyrosyl; N-L-tyrosyl-L-leucine; tyrosylleucine; L-Tyrosyl-L-leucine; L-Tyrosyl-L-leucin; H-TYR-LEU-OH; L-tyrosine-L-leucine; TYR-LEU CRYSTALLINE |
| Molecular Formula | C15H22N2O4 |
| Molecular Weight | 196.63 |
| Purity | 96+ |
| Density | 1.218g/cm3 |
| Boiling Point | 575.9ºC at 760 mmHg |
| Appearance | powder |
| Application | Tyr-Leu (YL) is an orally active dipeptide with powerful antidepressant activity [1]. |
| EINECS | 0 |
| HTC | 2924299090 |
| UN(IATA) | 0 |
| PubChem ID | 24891130 |
| MDL Number | MFCD00043020 |
| SMILES | Cl[H].NCCO\C=C\[C@H](N)C(O)=O |
| InChI | 1S/C6H12N2O3.ClH/c7-2-4-11-3-1-5(8)6(9)10;/h1,3,5H,2,4,7-8H2,(H,9,10);1H/b3-1+;/t5-;/m0./s1 |
| InChI Key | ZDCPLYVEFATMJF-BTIOQYSDSA-N |
| Beilstein/REAXYS | 6715149 |
| NACRES Code | NA.72 |
| UNSPSC | 10171502 |
| MSDS | msds/101025_1_17355_10_1.pdf |
| Use of | Tyrosylleucine (Tyr-Leu, YL), an orally active dipeptide, exhibits a potent antidepressant-like activity[1]. Properties Name Tyr-Leu Synonym More Synonyms Tyrosylleucine Biological Activity Description Tyrosylleucine (Tyr-Leu, YL), an orally active dipeptide, exhibits a potent antidepressant-like activity[1]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. Takafumi Mizushige, et al. Dipeptide tyrosyl-leucine exhibits antidepressant-like activity in mice. Sci Rep. 2020 Feb 10;10(1):2257. [2]. Norimasa Kanegawa, et al. Dipeptide Tyr-Leu (YL) exhibits anxiolytic-like activity after oral administration via activating serotonin 5-HT1A, dopamine D1 and GABAA receptors in mice. FEBS Lett. 2010 Feb 5;584(3):599-604. Chemical & Physical Properties Molecular Formula C15H22N2O4 Exact Mass 294.15800 PSA 112.65000 LogP 1.96870 Index of Refraction 1.565 InChIKey AUEJLPRZGVVDNU-STQMWFEESA-N Safety Information WGK Germany 3 HS Code 2924299090 Precursor & DownStream Precursor 1 CAS#:35971-70-1 Z-Tyr-Leu-OH DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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