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Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > (E)-ETHYL (3-(4-((3-METHYL-4-((6-METHYLPYRIDIN-3-YL)OXY)PHENYL)AMINO)QUINAZOLIN-6-YL)ALLYL)CARBAMATE

(E)-ETHYL (3-(4-((3-METHYL-4-((6-METHYLPYRIDIN-3-YL)OXY)PHENYL)AMINO)QUINAZOLIN-6-YL)ALLYL)CARBAMATE

CAS Number537705-08-1

SynonymsKumarin; Rattex; CUMARIN; COUMARINE; chromen-2-one

Molecular FormulaC27H27O3N5

Molecular Weight469.54

Purity96+%

Density1.3±0.1 g/cm3

Boiling Point687.3±55.0 °C at 760 mmHg

Melting Point

Flash Point

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EINECS0

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Cat. No.: 2A-0098970 Purity: 96+%
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Quality Control of [ 537705-08-1 ] Purity: 96+% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number537705-08-1
Catalog No.2A-0098970
Chinese Name2-甲氧基-N-[3-[4-[[3-甲基-4-[(6-甲基-3-吡啶基)氧基]苯基]氨基]-6-喹唑啉基]-2-丙烯-1-基]乙酰胺
SynonymsKumarin; Rattex; CUMARIN; COUMARINE; chromen-2-one
Molecular FormulaC27H27O3N5
Molecular Weight469.54
Purity96+
Density1.3±0.1 g/cm3
Boiling Point687.3±55.0 °C at 760 mmHg
Storage Condition-20°C
Application(E/Z)-CP-724714 is the racemate of (E)-CP-724714 and (Z)-CP-724714. CP-724714 is a highly potent, selective, orally active ErbB2 (HER2) tyrosine kinase inhibitor.
EINECS0
HTC2933990090
UN(IATA)0
MDL NumberMFCD15144738
MSDSmsds/98970_1_537705_08_1.pdf
Use of(E/Z)-CP-724714 is a racemic compound of (E)-CP-724714 and (Z)-CP-724714 isomers. CP-724714 is a potent and selective orally active ErbB2 (HER2) inhibitor[1]. Properties Name (E)-Ethyl (3-(4-((3-methyl-4-((6-methylpyridin-3-yl)oxy)phenyl)amino)quinazolin-6-yl)allyl)carbamate Synonym More Synonyms CP-724714 Biological Activity Description (E/Z)-CP-724714 is a racemic compound of (E)-CP-724714 and (Z)-CP-724714 isomers. CP-724714 is a potent and selective orally active ErbB2 (HER2) inhibitor[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR References [1]. Jani JP, et al. Discovery and pharmacologic characterization of CP-724,714, a selective ErbB2 tyrosine kinase inhibitor. Cancer Res, 2007, 67(20), 9887-9893. Chemical & Physical Properties Molecular Formula C27H27N5O3 Exact Mass 469.211395 PSA 98.26000 Index of Refraction 1.663 Safety Information HS Code 2933990090
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport InfoProduct name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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