
CAS Number52214-84-3
Synonyms2-[p-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid; Ciprofibrate; 2-[p-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid,Ciprofibrate; EINECS 257-744-6; MFCD00467135; 2-(4-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid; 2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropionic Acid; UNII:F8252JGO9S; 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
Molecular FormulaC13H14Cl2O3
Molecular Weight289.15
Purity98%
Density1.4±0.1 g/cm3
Boiling Point424.9±45.0 °C at 760 mmHg
Melting Point114 - 118ºC
Appearancepowder
EINECS257-744-6
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 52214-84-3 |
| Catalog No. | 2A-9009817 |
| Chinese Name | 环丙贝特 |
| Synonyms | 2-[p-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid; Ciprofibrate; 2-[p-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid,Ciprofibrate; EINECS 257-744-6; MFCD00467135; 2-(4-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid; 2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropionic Acid; UNII:F8252JGO9S; 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid |
| Molecular Formula | C13H14Cl2O3 |
| Molecular Weight | 289.15 |
| Purity | 98 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 424.9±45.0 °C at 760 mmHg |
| Melting Point | 114 - 118ºC |
| Appearance | powder |
| Water Solubility | Soluble in: methanol |
| Storage Condition | 2-8°C |
| Application | Ciprofibrate is a PPAR agonist. |
| EINECS | 257-744-6 |
| HTC | 2918990090 |
| PubChem ID | 24278288 |
| MDL Number | MFCD00467135 |
| SMILES | CC(C)(Oc1ccc(cc1)C2CC2(Cl)Cl)C(O)=O |
| InChI | 1S/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,14)15/h3-6,10H,7H2,1-2H3,(H,16,17) |
| InChI Key | KPSRODZRAIWAKH-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/9817_1_52214_84_3.pdf |
| Bioactivity | Ciprofibrate is a peroxisome proliferator-activated receptor agonist.Target: PPARCiprofibrate is a hypolipidemic compound that can induce proliferation of peroxisomes in liver cells of rats. Known to be a PPARα (peroxisome proliferator-activated receptor α) agonist [1, 2]. Related Catalog Research Areas >> Cancer Target PPARα References [1]. Passilly, P., et al., Phosphorylation of peroxisome proliferator-activated receptor alpha in rat Fao cells and stimulation by ciprofibrate. Biochem Pharmacol, 1999. 58(6): p. 1001-8. [2]. Clemencet, M.C., et al., Differences in cell proliferation in rodent and human hepatic derived cell lines exposed to ciprofibrate. Cancer Lett, 2005. 222(2): p. 217-26. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 424.9±45.0 °C at 760 mmHg Melting Point 114 - 118ºC Molecular Formula C13H14Cl2O3 Molecular Weight 289.155 Flash Point 210.7±28.7 °C Exact Mass 288.032013 PSA 46.53000 LogP 2.87 Vapour Pressure 0.0±1.1 mmHg at 25°C Index of Refraction 1.579 InChIKey KPSRODZRAIWAKH-UHFFFAOYSA-N SMILES CC(C)(Oc1ccc(C2CC2(Cl)Cl)cc1)C(=O)O Storage condition 2-8°C |
| Use of | Ciprofibrate is a peroxisome proliferator-activated receptor agonist.Target: PPARCiprofibrate is a hypolipidemic compound that can induce proliferation of peroxisomes in liver cells of rats. Known to be a PPARα (peroxisome proliferator-activated receptor α) agonist [1, 2]. Properties Articles31 Name ciprofibrate Synonym More Synonyms Ciprofibrate Biological Activity Description Ciprofibrate is a peroxisome proliferator-activated receptor agonist.Target: PPARCiprofibrate is a hypolipidemic compound that can induce proliferation of peroxisomes in liver cells of rats. Known to be a PPARα (peroxisome proliferator-activated receptor α) agonist [1, 2]. Related Catalog Research Areas >> Cancer References [1]. Passilly, P., et al., Phosphorylation of peroxisome proliferator-activated receptor alpha in rat Fao cells and stimulation by ciprofibrate. Biochem Pharmacol, 1999. 58(6): p. 1001-8. [2]. Clemencet, M.C., et al., Differences in cell proliferation in rodent and human hepatic derived cell lines exposed to ciprofibrate. Cancer Lett, 2005. 222(2): p. 217-26. Chemical & Physical Properties Exact Mass 288.032013 PSA 46.53000 Index of Refraction 1.579 InChIKey KPSRODZRAIWAKH-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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