Chlorhexidine gluconate structure, CAS 18472-51-0

Chlorhexidine gluconate

CAS Number18472-51-0

SynonymsMaskin; Unisept; Chlorhexamed; 1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane; Septeal; Betasept; N,N''''-1,6-Hexanediylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)] - D-gluconic acid (1:2); N,N''-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide di-D-gluconate; Peridex; Rotersept; hibitane; Manusan; chlorohexidine digluconate; Chlorhexidin Bigluconate; MFCD00083599; Chlorhexidine gluconate; disteryl; chlorhexidine gigluconate; Hibident; Plurexid; Hibidil; N,N''''-Hexane-1,6-diylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)] - D-gluconic acid (1:2); 1,1'-Hexamethylenebis(5-[p-chlorophenyl]biguanide); chlorhexidine bigluconate; EINECS 242-354-0; STERILON; 4-CHLORHEXIDINE DIGLUCONATE; Corsodyl; chlorhexidine D-digluconate; chlorhexidine di-D-gluconate

Molecular FormulaC34H54Cl2N10O14

Molecular Weight897.757

Purity20%

Density1.06 g/mL at 25 °C(lit.)

Boiling Point699.3ºC at 760 mmHg

Melting Point134ºC

Flash Point

Appearanceliquid

EINECS

MSDSChineseEnglish

Symbol

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Cat. No.: 2A-9009733 Purity: 20%
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Quality Control of [ 18472-51-0 ] Purity: 20% SDS Specification MoL

Chemical & Physical Properties
CAS Number18472-51-0
Catalog No.2A-9009733
Chinese Name葡萄糖酸氯己定
SynonymsMaskin; Unisept; Chlorhexamed; 1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane; Septeal; Betasept; N,N''''-1,6-Hexanediylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)] - D-gluconic acid (1:2); N,N''-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide di-D-gluconate; Peridex; Rotersept; hibitane; Manusan; chlorohexidine digluconate; Chlorhexidin Bigluconate; MFCD00083599; Chlorhexidine gluconate; disteryl; chlorhexidine gigluconate; Hibident; Plurexid; Hibidil; N,N''''-Hexane-1,6-diylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)] - D-gluconic acid (1:2); 1,1'-Hexamethylenebis(5-[p-chlorophenyl]biguanide); chlorhexidine bigluconate; EINECS 242-354-0; STERILON; 4-CHLORHEXIDINE DIGLUCONATE; Corsodyl; chlorhexidine D-digluconate; chlorhexidine di-D-gluconate
Molecular FormulaC34H54Cl2N10O14
Molecular Weight897.757
Purity20
Density1.06 g/mL at 25 °C(lit.)
Boiling Point699.3ºC at 760 mmHg
Melting Point134ºC
Appearanceliquid
Storage ConditionClosed at room temperature, protected from light,
ApplicationChlorhexidine digluconate is an antimicrobial agent effective against both Gram-negative and Gram-positive bacteria.
HTC3004909090
PubChem ID329775206
MDL NumberMFCD00083599
SMILESOC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1
InChI1S/C22H30Cl2N10.2C6H12O7/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*7-1-2(8)3(9)4(10)5(11)6(12)13/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*2-5,7-11H,1H2,(H,12,13)/t;2*2-,3-,4+,5-/m.11/s1
InChI KeyYZIYKJHYYHPJIB-UUPCJSQJSA-N
NACRES CodeNA.85
UNSPSC51102829
MSDSmsds/9733_1_18472_51_0.pdf
BioactivityChlorhexidine is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms.Target: AntibacterialChlorhexidine is a chemical antiseptic.It is effective on both Gram-positive and Gram-negative bacteria, although it is less effective with some Gram-negative bacteria.It has both bactericidal and bacteriostatic mechanisms of action, the mechanism of action being membrane disruption, not ATPase inactivation as previously thought.It is also useful against fungi and enveloped viruses, though this has not been extensively investigated. Chlorhexidine is harmful in high concentrations, but is used safely in low concentrations in many products, such as mouthwash and contact lens solutions [1, 2]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Jenkins, S., M. Addy, and W. Wade, The mechanism of action of chlorhexidine. A study of plaque growth on enamel inserts in vivo. J Clin Periodontol, 1988. 15(7): p. 415-24. [2]. Maki, D.G., M. Ringer, and C.J. Alvarado, Prospective randomised trial of povidone-iodine, alcohol, and chlorhexidine for prevention of infection associated with central venous and arterial catheters. Lancet, 1991. 338(8763): p. 339-43. Chemical & Physical Properties Density 1.06 g/mL at 25 °C(lit.) Boiling Point 699.3ºC at 760 mmHg Melting Point 134ºC Molecular Formula C34H54Cl2N10O14 Molecular Weight 897.757 Flash Point 376.7ºC Exact Mass 896.319824 PSA 444.48000 Vapour Pressure 0mmHg at 25°C InChIKey YZIYKJHYYHPJIB-UUPCJSQJSA-N SMILES NC(=NCCCCCCN=C(N)N=C(N)Nc1ccc(Cl)cc1)N=C(N)Nc1ccc(Cl)cc1.O=C(O)C(O)C(O)C(O)C(O)CO.O=C(O)C(O)C(O)C(O)C(O)CO
Use ofChlorhexidine is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms.Target: AntibacterialChlorhexidine is a chemical antiseptic.It is effective on both Gram-positive and Gram-negative bacteria, although it is less effective with some Gram-negative bacteria.It has both bactericidal and bacteriostatic mechanisms of action, the mechanism of action being membrane disruption, not ATPase inactivation as previously thought.It is also useful against fungi and enveloped viruses, though this has not been extensively investigated. Chlorhexidine is harmful in high concentrations, but is used safely in low concentrations in many products, such as mouthwash and contact lens solutions [1, 2]. Properties Articles23 Name chlorhexidine gluconate Synonym More Synonyms Chlorhexidine digluconate Biological Activity Description Chlorhexidine is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms.Target: AntibacterialChlorhexidine is a chemical antiseptic.It is effective on both Gram-positive and Gram-negative bacteria, although it is less effective with some Gram-negative bacteria.It has both bactericidal and bacteriostatic mechanisms of action, the mechanism of action being membrane disruption, not ATPase inactivation as previously thought.It is also useful against fungi and enveloped viruses, though this has not been extensively investigated. Chlorhexidine is harmful in high concentrations, but is used safely in low concentrations in many products, such as mouthwash and contact lens solutions [1, 2]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Jenkins, S., M. Addy, and W. Wade, The mechanism of action of chlorhexidine. A study of plaque growth on enamel inserts in vivo. J Clin Periodontol, 1988. 15(7): p. 415-24. [2]. Maki, D.G., M. Ringer, and C.J. Alvarado, Prospective randomised trial of povidone-iodine, alcohol, and chlorhexidine for prevention of infection associated with central venous and arterial catheters. Lancet, 1991. 338(8763): p. 339-43. Chemical & Physical Properties Exact Mass 896.319824 PSA 444.48000 InChIKey YZIYKJHYYHPJIB-UUPCJSQJSA-N
Transport InfoProduct Name: Chlorhexidine Gluconate
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